Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 3/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8947253 | 0.82 | NPC1 (0.46) | DHODHACMSDNPC1RAB9AMEN1 | |
| SCHEMBL8947243 | 0.76 | PIN1 (0.49) | DHODHPIM1KDM4EFAAH | |
| SCHEMBL17960860 | 0.75 | ADORA3 (0.54) | NPC1RAB9AMEN1KMT2AADORA3 | |
| SCHEMBL8947213 | 0.75 | LMNA (0.49) | NPC1RAB9AMEN1KMT2AFAAH | |
| SCHEMBL8804128 | 0.72 | NPC1 (0.34) | TTRPIM1PIM3KDM4ENPC1 | |
| SCHEMBL18377841 | 0.72 | ADORA3 (0.53) | TTRPIM1PIM3KDM4EALOX15 | |
| SCHEMBL8947224 | 0.71 | FABP4 (0.35) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL18378935 | 0.71 | MEN1 (0.56) | NPC1RAB9ATHRBMEN1KMT2A | |
| SCHEMBL27508760 | 0.70 | CYP19A1 (0.48) | ALOX15TSHRNPC1RAB9AMEN1 | |
| SCHEMBL3647705 | 0.68 | SMN1; SMN2 (0.56) | KDM4EALOX15TSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583092-A | PLANT ANTIGROWTH AGENTS | AMERICAN CYANAMID COMPANY (US) | 1996-12-10 | — | — | US | disclosed |
| EP-0726261-A1 | Herbidical 1,2,4 thiadiazoles | American Cyanamid Company (US) | 1996-08-14 | — | — | EP | disclosed |
| EP-0726260-A1 | Herbicidal (1,2,4)thiadiazoles | AMERICAN CYANAMID COMPANY (US) | 1996-08-14 | — | — | EP | disclosed |