Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | CASP6 | P55212 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.39 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8947532 | 0.89 | CASP6 (0.43) | CA2CA1CA9CASP6KDM4E | |
| SCHEMBL8947597 | 0.83 | CASP6 (0.43) | CA2CA1CA9CASP6KDM4E | |
| SCHEMBL3830815 | 0.81 | RAPGEF4 (0.59) | CA2CA1CA9CASP6KDM4E | |
| SCHEMBL16015147 | 0.79 | KMT2A (0.48) | CA2CA1CA9CASP6KDM4E | |
| SCHEMBL27849573 | 0.78 | CA1 (0.58) | CA2CA1CA9KDM4ESMN1; SMN2 | |
| SCHEMBL9644847 | 0.78 | CASP6 (0.46) | CA2CA1CA9CASP6KDM4E | |
| SCHEMBL27901102 | 0.78 | CA1 (0.56) | CA2CA1CA9KDM4ESMN1; SMN2 | |
| SCHEMBL27901098 | 0.78 | CA1 (0.56) | CA2CA1CA9KDM4ESMN1; SMN2 | |
| SCHEMBL10958088 | 0.76 | MEN1 (0.53) | CA2CA1CA9CASP6KDM4E | |
| SCHEMBL29564545 | 0.76 | CA2 (0.52) | CA2CA1CA9CASP6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512663-A | Disazo reactive dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-30 | — | — | US | disclosed |
| EP-0622424-A1 | Reactive dyes | BAYER AG (DE) | 1994-11-02 | — | — | EP | disclosed |