Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 6/20 | 0.34 |
| ▸ | FAAH | O00519 | 8/20 | 0.32 |
| ▸ | CES2 | O00748 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3628918 | 0.93 | CPA1 (0.38) | CPA1CES1FAAHCES2MEN1 | |
| SCHEMBL20995341 | 0.73 | FAAH (0.38) | CPA1CES1FAAHCES2MEN1 | |
| Trifluoroacetic Acid SCHEMBL5493316 | 0.71 | RNPEP (0.36) | MEN1KMT2AHSD17B10 | |
| Trifluoroacetic Acid SCHEMBL7814389 | 0.69 | ALDH1A1 (0.44) | CES1FAAHMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL30657022 | 0.69 | — | — | |
| Trifluoroacetic Acid SCHEMBL474 | 0.69 | — | — | |
| Trifluoroacetic Acid SCHEMBL4598430 | 0.69 | — | — | |
| Trifluoroacetic Acid SCHEMBL2484766 | 0.69 | ALDH1A1 (0.44) | CES1FAAHMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL449641 | 0.69 | RNPEP (0.35) | MEN1KMT2AHSD17B10 | |
| Trifluoroacetic Acid SCHEMBL21522569 | 0.68 | ALDH1A1 (0.35) | CES1MEN1KMT2AACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120082619-A1 | Labelled adrenomedullin derivatives and their use for imaging and therapy | PULMOSCIENCE INC. (CA) | 2012-04-05 | — | — | US | disclosed |
| EP-1749026-B1 | LABELLED ADRENOMEDULLIN DERIVATIVES AND THEIR USE FOR IMAGING AND THERAPY | INST CARDIOLOGIE MONTREAL (CA) | 2011-11-23 | — | — | EP | disclosed |