Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 10/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8947918 | 0.77 | TACR1 (0.52) | TACR1LMNADPP4 | |
| SCHEMBL8785081 | 0.76 | TACR1 (0.58) | TACR1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL8936490 | 0.74 | TACR1 (0.73) | TACR1 | |
| SCHEMBL8784483 | 0.74 | TACR1 (0.56) | TACR1DPP4 | |
| SCHEMBL8947993 | 0.74 | DPP4 (0.71) | TACR1DPP4 | |
| SCHEMBL8786372 | 0.74 | TACR1 (0.51) | TACR1DPP4 | |
| SCHEMBL5236388 | 0.72 | DPP4 (0.70) | TACR1DPP4 | |
| SCHEMBL8784402 | 0.71 | KCNA5 (0.55) | TACR1SMN1; SMN2DPP4 | |
| SCHEMBL8785655 | 0.71 | TACR1 (0.56) | TACR1LMNASMN1; SMN2HTT | |
| Benzyl Phenethylcarbamate SCHEMBL4287199 | 0.69 | LMNA (0.73) | L3MBTL1LMNASMN1; SMN2IDO1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527811-A | CALCIUM- AND SUBSTANCE P RECEPTOR-ANTAGONIST ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-06-18 | — | — | US | disclosed |
| EP-0634402-A1 | Isochinolinone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1995-01-18 | — | — | EP | disclosed |