SCHEMBL894810

SCHEMBL894810

NC(=O)c1cccc([N+](=O)[O-])c1O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 2/20 0.64
ERN1 O75460 1/20 0.51
CRHBP P24387 2/20 0.51
CRHR2 Q13324 2/20 0.51
TSHR P16473 3/20 0.50
CTSD P07339 1/20 0.50
P2RX1 P51575 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
ALDH1A1 P00352 3/20 0.49
TDP1 Q9NUW8 2/20 0.45
CXCR1 P25024 1/20 0.45
CXCR2 P25025 1/20 0.45
LMNA P02545 1/20 0.45
G6PD P11413 1/20 0.44
KCNMA1 Q12791 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11306178 0.85 GPR35 (0.69) GPR35ERN1CRHBPCRHR2TSHR
SCHEMBL29642497 0.84 GPR35 (0.62) GPR35ERN1CRHBPCRHR2TSHR
SCHEMBL20501861 0.84 GPR35 (0.62) GPR35ERN1CRHBPCRHR2TSHR
SCHEMBL71887 0.83 GPR35 (0.67) GPR35ERN1CRHBPCRHR2TSHR
SCHEMBL1456960 0.83 GPR35 (0.67) GPR35ERN1CRHBPCRHR2TSHR
SCHEMBL1340066 0.83 GPR35 (0.67) GPR35ERN1CRHBPCRHR2TSHR
SCHEMBL115478 0.82 CTSD (0.65) TSHRCTSDL3MBTL1ALDH1A1TDP1
SCHEMBL10766788 0.82 CTSD (0.65) TSHRCTSDL3MBTL1ALDH1A1TDP1
SCHEMBL7539226 0.82 CTSD (0.75) GPR35ERN1CRHBPCRHR2TSHR
SCHEMBL1315874 0.81 TDP1 (0.50) GPR35TSHRCTSDL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0970057-B1 SUBSTITUTED AMINOSALICYCLIC ACID AMIDES WITH FUNGICIDAL EFFECT AND INTERMEDIATE PRODUCTS FOR PRODUCTION THEREOF BAYER CROPSCIENCE AG (DE) 2006-02-01 EP claimed
EP-0848700-B1 ACYLAMINOSALICYLIC ACID AMIDES AND THEIR USES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2003-07-02 EP claimed
US-20020006958-A1 Substituted aminosalicylic acid amides with fungicidal effect and intermediate products for production thereof BAYER INTELLECTUAL PROPERTY GMBH (DE) 2002-01-17 US claimed
US-6297401-B1 A 3-NITROSALICYLAMIDE DERIVATIVE EFFECTIVE AGAINST PLANT PYTOPATHOGENS DOW AGROSCIENCES LLC 2001-10-02 US claimed
EP-1035772-A4 FUNGICIDAL COMPOSITIONS AND METHODS, AND COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF DOW AGROSCIENCES LLC (US) 2001-03-28 EP claimed
US-6194418-B1 Substituted aminosalicyclic acid amides with fungicidal effect and intermediate products for production thereof BAYER AKTIENGESELLSCHAFT (DE) 2001-02-27 US claimed
EP-1035772-A1 FUNGICIDAL COMPOSITIONS AND METHODS, AND COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF Dow AgroSciences LLC (US) 2000-09-20 EP claimed
US-6001879-A SUITABLE FOR CONTROLLING PESTS, PREFERABLY FUNGI, INSECTS AND BACTERIA, IN PLANTS AND INDUSTRIAL MATERIALS; METHODS OF THEIR SYBNTHESIS INCLUDING REACTING AMINOSALICYLAMIDES WITH ACYLATING AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1999-12-14 US claimed
WO-1999027783-A1 FUNGICIDAL COMPOSITIONS AND METHODS, AND COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF DOW AGROSCIENCES LLC (US) 1999-06-10 WO claimed
JP-1009980-A None JP disclosed
US-12454507-B2 Compounds having a fungicidal activity, their agronomic compositions and use thereof for the control of phytopathogenic fungi ISAGRO SPA (IT) 2025-10-28 US disclosed
US-20250243193-A1 AMIDE-SUBSTITUTED HETEROCYCLIC COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFN ALPHA RESPONSES SYNGENE INTERNATIONAL LIMITED (IN) 2025-07-31 US disclosed
US-20240116855-A1 COMPOUNDS HAVING A FUNGICIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND USE THEREOF FOR THE CONTROL OF PHYTOPATHOGENIC FUNGI ISAGRO S.P.A. (IT) 2024-04-11 US disclosed
EP-4162799-A1 COMPOUNDS HAVING A FUNGICIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND USE THEREOF FOR THE CONTROL OF PHYTOPATHOGENIC FUNGI ISAGRO S.p.A. (IT) 2023-04-12 EP disclosed
US-6194418-B1 Substituted aminosalicyclic acid amides with fungicidal effect and intermediate products for production thereof BAYER AKTIENGESELLSCHAFT (DE) 2001-02-27 US disclosed
EP-1035772-A1 FUNGICIDAL COMPOSITIONS AND METHODS, AND COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF Dow AgroSciences LLC (US) 2000-09-20 EP disclosed
EP-1035772-A1 FUNGICIDAL COMPOSITIONS AND METHODS, AND COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF Dow AgroSciences LLC (US) 2000-09-20 EP disclosed
US-6001879-A SUITABLE FOR CONTROLLING PESTS, PREFERABLY FUNGI, INSECTS AND BACTERIA, IN PLANTS AND INDUSTRIAL MATERIALS; METHODS OF THEIR SYBNTHESIS INCLUDING REACTING AMINOSALICYLAMIDES WITH ACYLATING AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1999-12-14 US disclosed
WO-1999027783-A1 FUNGICIDAL COMPOSITIONS AND METHODS, AND COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF DOW AGROSCIENCES LLC (US) 1999-06-10 WO disclosed
WO-1999027783-A1 FUNGICIDAL COMPOSITIONS AND METHODS, AND COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF DOW AGROSCIENCES LLC (US) 1999-06-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240116855-A1 COMPOUNDS HAVING A FUNGICIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND USE THEREOF FOR THE CONTROL OF PHYTOPATHOGENIC FUNGI CYP51A1, ERG28, DPM1 GPR35 3996/4885ERN1 1953/4885CRHBP 4834/4885
US-20250243193-A1 AMIDE-SUBSTITUTED HETEROCYCLIC COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFN ALPHA RESPONSES IFNG, IFNAR1, TYK2 GPR35 1270/4885ERN1 673/4885CRHBP 3180/4885
US-20020006958-A1 Substituted aminosalicylic acid amides with fungicidal effect and intermediate products for production thereof AADAC, DDC, DAO GPR35 4093/4885ERN1 4212/4885CRHBP 4756/4885
US-12454507-B2 Compounds having a fungicidal activity, their agronomic compositions and use thereof for the control of phytopathogenic fungi CYP51A1, ERG28, DPM1 GPR35 3996/4885ERN1 1953/4885CRHBP 4834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.