Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.38 |
| ▸ | PTGES | O14684 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8718692 | 0.74 | KMT2A (0.36) | NLRP3ALDH1A1KMT2ANPC1CYP1A2 | |
| SCHEMBL7558526 | 0.72 | NLRP3 (0.54) | NLRP3ALDH1A1KMT2ANPC1CYP1A2 | |
| SCHEMBL7562049 | 0.71 | KCNQ3 (0.45) | NLRP3ALDH1A1KMT2ANPC1CYP1A2 | |
| SCHEMBL11046716 | 0.68 | NLRP3 (0.44) | NLRP3ALDH1A1KMT2ANPC1CYP1A2 | |
| SCHEMBL8948747 | 0.68 | HTR2A (0.33) | PTGESALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7662875 | 0.68 | KCNQ3 (0.42) | NLRP3ALDH1A1KMT2ANPC1CYP1A2 | |
| SCHEMBL8691257 | 0.68 | KDM4E (0.40) | NLRP3ALDH1A1SCN9ASCN5AKMT2A | |
| SCHEMBL7557601 | 0.67 | ALDH1A1 (0.42) | NLRP3ALDH1A1KMT2ANPC1CYP1A2 | |
| SCHEMBL5397703 | 0.67 | ALDH1A1 (0.42) | NLRP3ALDH1A1KMT2ANPC1CYP1A2 | |
| SCHEMBL7220721 | 0.67 | ALDH1A1 (0.54) | ALDH1A1NPC1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521147-A | HERBICIDES | FMC CORPORATION (US) | 1996-05-28 | — | — | US | disclosed |
| WO-1995005079-A1 | 3-(BENZOFURAN-7-YL)-6-HALOALKYLURACILS | FMC CORPORATION (US) | 1995-02-23 | — | — | WO | disclosed |