Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 8/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948766 | 0.92 | GRM2 (0.44) | SIGMAR1GRM2L3MBTL1FNTAFNTB | |
| SCHEMBL8948876 | 0.91 | SIGMAR1 (0.43) | SIGMAR1GRM2L3MBTL1ITGB3ITGA2B | |
| SCHEMBL8450620 | 0.89 | GRM2 (0.42) | SIGMAR1DRD4TMEM97GRM2L3MBTL1 | |
| SCHEMBL8948657 | 0.89 | GRM2 (0.47) | SIGMAR1DRD4TMEM97GRM2ITGB3 | |
| SCHEMBL8948674 | 0.87 | GRM2 (0.46) | SIGMAR1DRD4TMEM97GRM2 | |
| SCHEMBL8948592 | 0.87 | GRM2 (0.42) | SIGMAR1GRM2L3MBTL1ITGB3ITGA2B | |
| SCHEMBL8948686 | 0.85 | L3MBTL1 (0.47) | SIGMAR1GRM2L3MBTL1 | |
| SCHEMBL8948850 | 0.85 | GRM2 (0.44) | SIGMAR1DRD4TMEM97GRM2ITGB3 | |
| SCHEMBL8948780 | 0.83 | ITGB3 (0.51) | SIGMAR1GRM2L3MBTL1FNTAFNTB | |
| SCHEMBL8948773 | 0.83 | SIGMAR1 (0.44) | SIGMAR1GRM2L3MBTL1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |