Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948809 | 0.85 | TSHR (0.43) | TSHRMAPK1LMNAMAPTKMT2A | |
| SCHEMBL8948559 | 0.77 | MAPK1 (0.58) | TSHRMAPK1SLC22A6LMNAMAPT | |
| SCHEMBL11631680 | 0.73 | MAPK1 (0.58) | TSHRMAPK1SLC22A6LMNAMAPT | |
| SCHEMBL8009914 | 0.70 | LMNA (0.45) | TSHRMAPK1LMNA | |
| SCHEMBL9289522 | 0.67 | HCAR3 (0.41) | TSHRMAPK1LMNAMAPT | |
| SCHEMBL11637395 | 0.66 | TSHR (0.53) | TSHRMAPK1LMNAMAPTKMT2A | |
| SCHEMBL11441037 | 0.66 | HCAR3 (0.38) | TSHRMAPK1LMNAMAPT | |
| SCHEMBL15489154 | 0.66 | SMN1; SMN2 (0.38) | TSHRMAPK1LMNA | |
| SCHEMBL4587818 | 0.65 | TPMT (0.41) | TSHRMAPK1LMNAKMT2A | |
| SCHEMBL8948857 | 0.65 | LMNA (0.46) | TSHRMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5569446-A | Radiohalogenation of proteins using trihalophenyl derivatives | BRACCO INTERNATIONAL B.V. | 1996-10-29 | — | — | US | disclosed |
| US-5463080-A | 2,4,6-triiodo-1,3-benzenedicarboxylic acid compounds used as radiolabelling reagents | BRACCO INTERNATIONAL B.V. (NL) | 1995-10-31 | — | — | US | disclosed |