Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | IL1B | P01584 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | VCP | P55072 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949075 | 1.00 | ITGB3 (0.43) | ITGB3ITGA2BHCAR3PDK1ACHE | |
| SCHEMBL8949216 | 0.88 | PDGFRB (0.43) | ITGB3ITGA2BHCAR3PDK1ACHE | |
| SCHEMBL8949224 | 0.88 | PDGFRB (0.43) | ITGB3ITGA2BHCAR3PDK1ACHE | |
| SCHEMBL9571676 | 0.85 | ITGB3 (0.46) | ITGB3ITGA2BPDK1ACHEDGAT1 | |
| Hydrochloric Acid SCHEMBL8949349 | 0.81 | ITGB3 (0.44) | ITGB3ITGA2BHCAR3PDK1ACHE | |
| SCHEMBL29818171 | 0.78 | ACHE (0.52) | PDK1ACHEIL1BNLRP3VCP | |
| SCHEMBL8949306 | 0.76 | ITGB3 (0.46) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL8949315 | 0.76 | ITGB3 (0.46) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL9252818 | 0.74 | ADORA3 (0.41) | ITGB3ITGA2BHCAR3DGAT1KCNH2 | |
| SCHEMBL9095484 | 0.74 | MEN1 (0.61) | ITGB3ITGA2BPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563268-A | FOR PREVENTING CELL AGGLOMERATION, TREATING THROMBOSIS, ARTERIOSCLEROSIS, BRAIN, LUNG OR CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-10-08 | — | — | US | disclosed |
| US-5418233-A | FOR INHIBITING CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1995-05-23 | — | — | US | disclosed |
| EP-0537696-A1 | Heterobiaryl derivatives, medicines containing those compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-04-21 | — | — | EP | disclosed |