Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 2/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 3/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.40 |
| ▸ | TMPRSS15 | P98073 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949224 | 1.00 | PDGFRB (0.43) | PDGFRBPDGFRAF2F10ITGB3 | |
| SCHEMBL8949083 | 0.88 | ITGB3 (0.43) | ITGB3ITGA2BPDK1ACHEHCAR3 | |
| SCHEMBL8949075 | 0.88 | ITGB3 (0.43) | ITGB3ITGA2BPDK1ACHEHCAR3 | |
| Hydrochloric Acid SCHEMBL8949349 | 0.84 | ITGB3 (0.44) | ITGB3ITGA2BHPGDRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8949208 | 0.83 | HCAR3 (0.46) | PDGFRBPDGFRAF2F10TMPRSS15 | |
| SCHEMBL8949227 | 0.81 | PDGFRB (0.43) | PDGFRBPDGFRAHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL8949232 | 0.81 | PDGFRB (0.43) | PDGFRBPDGFRAHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL9571676 | 0.80 | ITGB3 (0.46) | ITGB3ITGA2BPDK1ACHE | |
| Hydrochloric Acid SCHEMBL8949354 | 0.79 | ITGB3 (0.41) | F2F10ITGB3ITGA2BTMPRSS15 | |
| SCHEMBL29817860 | 0.78 | ACHE (0.48) | PDGFRBPDGFRAHPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563268-A | FOR PREVENTING CELL AGGLOMERATION, TREATING THROMBOSIS, ARTERIOSCLEROSIS, BRAIN, LUNG OR CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-10-08 | — | — | US | disclosed |
| US-5418233-A | FOR INHIBITING CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1995-05-23 | — | — | US | disclosed |
| EP-0537696-A1 | Heterobiaryl derivatives, medicines containing those compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-04-21 | — | — | EP | disclosed |