Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255137 | 0.91 | TMPRSS15 (0.41) | ADORA3ADORA1ITGB3ITGA2BTMPRSS15 | |
| SCHEMBL9254810 | 0.86 | VCP (0.41) | ITGB3ITGA2BSYKHSD11B1 | |
| SCHEMBL9251783 | 0.80 | TMPRSS15 (0.45) | ITGB3ITGA2BTMPRSS15PRSS1PRSS2 | |
| SCHEMBL9256431 | 0.78 | ITGB3 (0.38) | ITGB3ITGA2BTMPRSS15PRSS1PRSS2 | |
| SCHEMBL9249034 | 0.77 | TMPRSS15 (0.40) | KCNH2TMPRSS15PRSS1PRSS2PRSS3 | |
| SCHEMBL9251663 | 0.76 | TMPRSS15 (0.39) | ITGB3ITGA2BTMPRSS15PRSS1PRSS2 | |
| SCHEMBL8949083 | 0.74 | ITGB3 (0.43) | ITGB3ITGA2BDGAT1KCNH2PRSS1 | |
| SCHEMBL8949075 | 0.74 | ITGB3 (0.43) | ITGB3ITGA2BDGAT1KCNH2PRSS1 | |
| SCHEMBL9249043 | 0.72 | TMPRSS15 (0.40) | ADORA3ADORA1ITGB3ITGA2BTMPRSS15 | |
| SCHEMBL9253758 | 0.70 | ITGB3 (0.47) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |
| EP-0531883-A1 | Condensed 5-membered ring heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-03-17 | — | — | EP | disclosed |