Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.63 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.60 |
| ▸ | PTGES | O14684 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | RGS12 | O14924 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949442 | 0.93 | PLA2G2A (0.56) | PTGS2PLA2G2APTGESALOX5LMNA | |
| SCHEMBL8292054 | 0.93 | PLA2G2A (0.70) | PTGS2PLA2G2ALMNAMAPTPKM | |
| SCHEMBL8877441 | 0.90 | PTGS2 (0.79) | PTGS2PLA2G2ALMNACYP1A2CYP3A4 | |
| SCHEMBL9230125 | 0.85 | PTGS2 (0.79) | PTGS2PLA2G2APTGESALOX5LMNA | |
| SCHEMBL8292841 | 0.85 | PLA2G2A (0.60) | PTGS2PLA2G2ALMNAMAPTPKM | |
| SCHEMBL8291608 | 0.84 | PLA2G2A (0.60) | PTGS2PLA2G2ALMNATSHRMAPT | |
| SCHEMBL8296317 | 0.83 | LMNA (0.69) | PTGS2PLA2G2ALMNACYP1A2CYP3A4 | |
| SCHEMBL8291567 | 0.82 | PLA2G2A (0.61) | PTGS2PLA2G2ALMNAMAPTPKM | |
| SCHEMBL27905714 | 0.82 | PTGS2 (0.64) | PTGS2PLA2G2APTGESALOX5LMNA | |
| SCHEMBL8292611 | 0.81 | PLA2G2A (0.60) | PLA2G2ALMNAMAPTPKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510368-A | INHIBITORS OF CYCLOOXYGENASE | MERCK FROSST CANADA, INC. (CA) | 1996-04-23 | — | — | US | disclosed |