SCHEMBL8949511

SCHEMBL8949511

O=S(=O)(O)c1ccc(C(F)(F)F)c(C(F)(F)F)c1.[NaH]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
HSD17B10 Q99714 4/20 0.41
KIF11 P52732 3/20 0.41
PTPN11 Q06124 1/20 0.40
LMNA P02545 1/20 0.40
TSHR P16473 3/20 0.39
NT5E P21589 1/20 0.39
TDP1 Q9NUW8 2/20 0.38
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38
RXRG P48443 1/20 0.38
MEP1B Q16820 1/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA7 P43166 1/20 0.37
CA14 Q9ULX7 1/20 0.37
CYP2C9 P11712 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL370204 0.98 ALDH1A1 (0.42) ALDH1A1HSD17B10KIF11PTPN11LMNA
SCHEMBL12406442 0.87 KIF11 (0.41) ALDH1A1HSD17B10KIF11PTPN11LMNA
SCHEMBL11772110 0.83 NOTUM (0.45) ALDH1A1HSD17B10KIF11PTPN11LMNA
SCHEMBL3193910 0.82 KIF11 (0.56) ALDH1A1HSD17B10KIF11PTPN11LMNA
SCHEMBL3189180 0.82 ERAP1 (0.46) ALDH1A1HSD17B10KIF11PTPN11LMNA
SCHEMBL20752520 0.81 KIF11 (0.44) ALDH1A1KIF11LMNATSHRRXRA
SCHEMBL11516738 0.81 ALDH1A1 (0.56) ALDH1A1HSD17B10KIF11TSHRNT5E
Hydrochloric Acid SCHEMBL28095193 0.81 KIF11 (0.54) ALDH1A1HSD17B10KIF11PTPN11
SCHEMBL11243895 0.81 FFAR4 (0.54) ALDH1A1HSD17B10TSHRNT5ETDP1
SCHEMBL776654 0.81 TAS2R14 (0.39) ALDH1A1HSD17B10KIF11PTPN11LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5573708-A ACID-SUBSTITUTED PERFLUOROALKYLBENZENES UNION CHEMICAL CO., LTD. (JP) 1996-11-12 US claimed
EP-0569884-B1 Rust inhibitor UNION CHEMICAL CO LTD (JP) 1996-09-18 EP claimed
EP-0569884-A1 Rust inhibitor UNION CHEMICAL CO., LTD. (JP) 1993-11-18 EP claimed
EP-0569884-B1 Rust inhibitor UNION CHEMICAL CO LTD (JP) 1996-09-18 EP disclosed
US-5487846-A FLUORINE-SUBSTITUTED BENZENE DERIVATIVES UNION CHEMICAL CO., LTD. (JP) 1996-01-30 US disclosed
EP-0569884-A1 Rust inhibitor UNION CHEMICAL CO., LTD. (JP) 1993-11-18 EP disclosed