Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14947005 | 0.98 | ALDH1A1 (0.36) | ALDH1A1FAAHTSHR | |
| SCHEMBL9331605 | 0.89 | ALDH1A1 (0.39) | ALDH1A1TSHR | |
| SCHEMBL9335001 | 0.87 | ALDH1A1 (0.43) | ALDH1A1TSHR | |
| SCHEMBL6378882 | 0.85 | LMNA (0.32) | TSHR | |
| SCHEMBL9331501 | 0.84 | TSHR (0.42) | ALDH1A1TSHR | |
| SCHEMBL19285769 | 0.81 | CES2 (0.46) | ALDH1A1TSHR | |
| SCHEMBL19285720 | 0.79 | CES2 (0.48) | ALDH1A1TSHR | |
| SCHEMBL31187771 | 0.79 | CES2 (0.48) | ALDH1A1TSHR | |
| SCHEMBL8055772 | 0.78 | CES1 (0.44) | ALDH1A1FAAHTSHR | |
| SCHEMBL9331675 | 0.78 | ALDH1A1 (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574024-A | Methylene phosphonoalkylphosphinates, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism | EBETINO FRANK H (US) | 1996-11-12 | — | — | US | disclosed |
| EP-0298553-B1 | METHYLENE PHOSPHONOALKYLPHOSPHINATES, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | Norwich Eaton Pharmaceuticals, Inc. (US) | 1992-01-15 | — | — | EP | disclosed |
| EP-0298553-A1 | Methylene phosphonoalkylphosphinates, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism | Norwich Eaton Pharmaceuticals, Inc. (US) | 1989-01-11 | — | — | EP | disclosed |