SCHEMBL14947005

SCHEMBL14947005

COP(=O)(OC)C(=O)CCCCCCl

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
FAAH O00519 2/20 0.34
TSHR P16473 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8949937 0.98 ALDH1A1 (0.33) ALDH1A1FAAHTSHR
SCHEMBL9335001 0.89 ALDH1A1 (0.43) ALDH1A1TSHR
SCHEMBL9331605 0.87 ALDH1A1 (0.39) ALDH1A1TSHR
SCHEMBL6378882 0.83 LMNA (0.32) TSHR
SCHEMBL9331501 0.83 TSHR (0.42) ALDH1A1TSHR
SCHEMBL31187771 0.82 CES2 (0.48) ALDH1A1TSHR
SCHEMBL19285720 0.82 CES2 (0.48) ALDH1A1TSHR
SCHEMBL19285769 0.79 CES2 (0.46) ALDH1A1TSHR
SCHEMBL8055772 0.77 CES1 (0.44) ALDH1A1FAAHTSHR
SCHEMBL9331675 0.76 ALDH1A1 (0.32) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230285561-A1 Targeting Microbubbles CALIFORNIA INSTITUTE OF TECHNOLOGY 2023-09-14 US disclosed
US-20230285561-A1 Targeting Microbubbles CALIFORNIA INSTITUTE OF TECHNOLOGY 2023-09-14 US disclosed
US-11642410-B2 Targeting microbubbles CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2023-05-09 US disclosed
US-11642410-B2 Targeting microbubbles CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2023-05-09 US disclosed
US-11224655-B2 Targeting microbubbles CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2022-01-18 US disclosed
US-20190282695-A1 Targeting Microbubbles CALIFORNIA INSTITUTE OF TECHNOLOGY 2019-09-19 US disclosed
US-10357565-B2 Targeting microbubbles CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2019-07-23 US disclosed
US-20190038749-A1 TARGETING MICROBUBBLES CALIFORNIA INSTITUTE OF TECHNOLOGY 2019-02-07 US disclosed
US-20160367669-A1 TARGETING MICROBUBBLES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2016-12-22 US disclosed
US-20160367669-A1 TARGETING MICROBUBBLES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2016-12-22 US disclosed
US-20130123781-A1 TARGETING MICROBUBBLES CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2013-05-16 US disclosed
US-20130123781-A1 TARGETING MICROBUBBLES CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2013-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190282695-A1 Targeting Microbubbles PGF, EDNRB, FLT4 ALDH1A1 4587/4885FAAH 3016/4885TSHR 1669/4885
US-20130123781-A1 TARGETING MICROBUBBLES PGF, EDNRB, FLT4 ALDH1A1 4587/4885FAAH 3016/4885TSHR 1669/4885
US-11224655-B2 Targeting microbubbles PGF, EDNRB, FLT4 ALDH1A1 4587/4885FAAH 3016/4885TSHR 1669/4885
US-20190038749-A1 TARGETING MICROBUBBLES PGF, EDNRB, FLT4 ALDH1A1 4587/4885FAAH 3016/4885TSHR 1669/4885
US-10357565-B2 Targeting microbubbles PGF, EDNRB, FLT4 ALDH1A1 4587/4885FAAH 3016/4885TSHR 1669/4885
US-20230285561-A1 Targeting Microbubbles PGF, EDNRB, FLT4 ALDH1A1 4587/4885FAAH 3016/4885TSHR 1669/4885
US-20160367669-A1 TARGETING MICROBUBBLES PGF, EDNRB, FLT4 ALDH1A1 4587/4885FAAH 3016/4885TSHR 1669/4885
US-11642410-B2 Targeting microbubbles PGF, EDNRB, FLT4 ALDH1A1 4587/4885FAAH 3016/4885TSHR 1669/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.