Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 4/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8950204 | 0.83 | ABCB1 (0.41) | MAPTTHRBHCAR3PGRPOLB | |
| SCHEMBL8950320 | 0.83 | PGR (0.50) | MAPTPGRPOLB | |
| SCHEMBL7371675 | 0.80 | MAPT (0.67) | MAPTTHRBPGRMDM2POLB | |
| SCHEMBL7369772 | 0.80 | HCAR3 (0.61) | MAPTHCAR3POLBL3MBTL1MEN1 | |
| SCHEMBL7371356 | 0.73 | PGR (0.51) | MAPTPGRPOLBMEN1KMT2A | |
| SCHEMBL8775999 | 0.73 | CA12 (0.51) | PGRPOLBTDP1 | |
| SCHEMBL25403172 | 0.72 | PGR (0.63) | PGRPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL8950072 | 0.72 | ALDH1A1 (0.46) | MAPTHCAR3PGRPOLBL3MBTL1 | |
| SCHEMBL17846944 | 0.70 | L3MBTL1 (0.54) | MAPTHCAR3POLBL3MBTL1MEN1 | |
| SCHEMBL2976885 | 0.69 | MAPT (0.58) | MAPTHCAR3POLBL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534521-A | SEROTONIN ANTAGONISTS | G. D. SEARLE & CO. (US) | 1996-07-09 | — | — | US | disclosed |
| US-5521193-A | SEROTONIN AGONISTS AND ANTAGONISTS | G. D. SEARLE & CO. (US) | 1996-05-28 | — | — | US | disclosed |