Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8953797 | 0.88 | SIRT2 (0.33) | SIRT2PIP5K1CCCR2SMN1; SMN2LMNA | |
| SCHEMBL8953688 | 0.88 | SIRT2 (0.33) | SIRT2PIP5K1CCCR2SMN1; SMN2LMNA | |
| SCHEMBL8953786 | 0.85 | ALOX5 (0.44) | ALDH1A1PIP5K1CMGLLALOX5MEN1 | |
| SCHEMBL8953659 | 0.82 | SIRT2 (0.38) | SIRT2ALDH1A1CCR2SMN1; SMN2LMNA | |
| SCHEMBL8953864 | 0.80 | MAOB (0.47) | ALDH1A1KDM2BRAB9AKMT2A | |
| SCHEMBL8953684 | 0.78 | MTNR1A (0.34) | ALDH1A1CCR2SMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL8953680 | 0.78 | MTNR1A (0.34) | ALDH1A1CCR2SMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL8953842 | 0.77 | ALOX5 (0.35) | PIP5K1CSMN1; SMN2ALOX5 | |
| SCHEMBL8953770 | 0.73 | ALOX5 (0.41) | ALDH1A1PIP5K1CLMNAMGLLALOX5 | |
| SCHEMBL8953794 | 0.72 | PPARA (0.38) | ALDH1A1PIP5K1CKDM2BSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484786-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1996-01-16 | — | — | US | disclosed |