Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.44 |
| ▸ | MGLL | Q99685 | 13/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8953770 | 0.87 | ALOX5 (0.41) | ALOX5MGLLALDH1A1PIP5K1CKDM4E | |
| SCHEMBL8953605 | 0.85 | SIRT2 (0.37) | ALOX5MGLLALDH1A1PIP5K1CKDM4E | |
| SCHEMBL8953864 | 0.78 | MAOB (0.47) | ALDH1A1KMT2A | |
| SCHEMBL8953766 | 0.76 | ALOX5 (0.43) | ALOX5MGLLALDH1A1PIP5K1CKDM4E | |
| SCHEMBL8953763 | 0.76 | ALOX5 (0.43) | ALOX5MGLLALDH1A1PIP5K1CKDM4E | |
| SCHEMBL8953688 | 0.74 | SIRT2 (0.33) | ALOX5PIP5K1CKDM4EMEN1MAPT | |
| SCHEMBL8953797 | 0.74 | SIRT2 (0.33) | ALOX5PIP5K1CKDM4EMEN1MAPT | |
| SCHEMBL9380927 | 0.72 | ALOX5 (0.63) | ALOX5 | |
| SCHEMBL8953902 | 0.72 | HDAC3 (0.45) | ALOX5ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL8953794 | 0.69 | PPARA (0.38) | ALDH1A1PIP5K1CKDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484786-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1996-01-16 | — | — | US | disclosed |