Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.33 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 5/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ITK | Q08881 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8953688 | 1.00 | SIRT2 (0.33) | SIRT2PIP5K1CALOX5SMN1; SMN2LMNA | |
| SCHEMBL8953605 | 0.88 | SIRT2 (0.37) | SIRT2PIP5K1CALOX5SMN1; SMN2LMNA | |
| SCHEMBL8953842 | 0.87 | ALOX5 (0.35) | PIP5K1CALOX5SMN1; SMN2 | |
| SCHEMBL8953770 | 0.86 | ALOX5 (0.41) | PIP5K1CALOX5LMNAMAPTKDM4E | |
| SCHEMBL8953794 | 0.83 | PPARA (0.38) | PIP5K1CSMN1; SMN2LMNAHTTRAB9A | |
| SCHEMBL8953777 | 0.81 | MAOB (0.43) | RAB9AKMT2AGAA | |
| SCHEMBL8953702 | 0.81 | MAOB (0.43) | RAB9AKMT2AGAA | |
| SCHEMBL8953684 | 0.77 | MTNR1A (0.34) | ALOX5SMN1; SMN2RAB9AL3MBTL1CCR2 | |
| SCHEMBL8953680 | 0.77 | MTNR1A (0.34) | ALOX5SMN1; SMN2RAB9AL3MBTL1CCR2 | |
| SCHEMBL8953786 | 0.74 | ALOX5 (0.44) | PIP5K1CALOX5MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484786-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1996-01-16 | — | — | US | disclosed |