Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.41 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 7/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8953786 | 0.87 | ALOX5 (0.44) | ALOX5PIP5K1CMGLLMEN1KMT2A | |
| SCHEMBL8953688 | 0.86 | SIRT2 (0.33) | ALOX5PIP5K1CLMNAGAAMEN1 | |
| SCHEMBL8953797 | 0.86 | SIRT2 (0.33) | ALOX5PIP5K1CLMNAGAAMEN1 | |
| SCHEMBL8953794 | 0.80 | PPARA (0.38) | PIP5K1CHDAC1HDAC8HDAC6LMNA | |
| SCHEMBL8953702 | 0.79 | MAOB (0.43) | GAAKMT2AALDH1A1 | |
| SCHEMBL8953777 | 0.79 | MAOB (0.43) | GAAKMT2AALDH1A1 | |
| SCHEMBL8953842 | 0.75 | ALOX5 (0.35) | ALOX5PIP5K1C | |
| SCHEMBL8953763 | 0.75 | ALOX5 (0.43) | ALOX5PIP5K1CMGLLHDAC3HDAC4 | |
| SCHEMBL8953766 | 0.75 | ALOX5 (0.43) | ALOX5PIP5K1CMGLLHDAC3HDAC4 | |
| SCHEMBL8953605 | 0.73 | SIRT2 (0.37) | ALOX5PIP5K1CMGLLLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484786-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1996-01-16 | — | — | US | disclosed |