Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9310396 | 0.83 | ALOX5 (0.63) | ALOX5 | |
| SCHEMBL9307698 | 0.80 | ALOX5 (0.50) | ALOX5MRGPRX4RAB9AMAOB | |
| SCHEMBL8953741 | 0.77 | KMT2A (0.50) | NR4A2MAOBMEN1KMT2A | |
| SCHEMBL9000918 | 0.76 | ALOX5 (0.46) | ALOX5MRGPRX4RAB9AMCHR1MAOB | |
| SCHEMBL9308093 | 0.74 | MRGPRX4 (0.51) | ALOX5MRGPRX4NR4A2MAOB | |
| SCHEMBL9307724 | 0.73 | ALOX5 (0.45) | ALOX5 | |
| SCHEMBL9310760 | 0.73 | ALOX5 (0.66) | ALOX5 | |
| SCHEMBL8953638 | 0.73 | HRH3 (0.40) | ALOX5RAB9ANPC1NR4A2MAOB | |
| SCHEMBL9081307 | 0.73 | ALOX5 (0.52) | ALOX5MRGPRX4RAB9ANPC1MAPT | |
| SCHEMBL26358151 | 0.72 | MEN1 (0.73) | ALOX5MRGPRX4RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354865-A | Enzyme inhibitor and inhibiting the leukotriene biosynthesis | ABBOTT LABORATORIES (US) | 1994-10-11 | — | — | US | disclosed |
| WO-1994005281-A1 | PHENYLMETHYL DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LABORATORIES (US) | 1994-03-17 | — | — | WO | disclosed |