Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8953694 | 0.85 | RAB9A (0.41) | ALDH1A1RAB9A | |
| SCHEMBL8953698 | 0.85 | RAB9A (0.41) | ALDH1A1RAB9A | |
| SCHEMBL8953684 | 0.83 | MTNR1A (0.34) | MTNR1AMTNR1BGAAALDH1A1SRD5A1 | |
| SCHEMBL8953680 | 0.83 | MTNR1A (0.34) | MTNR1AMTNR1BGAAALDH1A1SRD5A1 | |
| SCHEMBL8953766 | 0.80 | ALOX5 (0.43) | MTNR1AMTNR1BALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL8953763 | 0.80 | ALOX5 (0.43) | MTNR1AMTNR1BALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL8953666 | 0.77 | ALOX5 (0.37) | PPARARXRA | |
| SCHEMBL8953670 | 0.77 | ALOX5 (0.37) | PPARARXRA | |
| SCHEMBL8953794 | 0.76 | PPARA (0.38) | PPARAGAAALDH1A1NR1H4RXRA | |
| SCHEMBL8953733 | 0.75 | ALOX5 (0.35) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484786-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1996-01-16 | — | — | US | disclosed |