SCHEMBL8953849

SCHEMBL8953849

COC(c1cc(F)cc(SCc2ccc(N(C)C(C)=S)cc2)c1)C1CCOCC1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8953700 0.91 ALOX5 (0.40) ALOX5
SCHEMBL8953855 0.78 RORC (0.31)
SCHEMBL8953916 0.74 ALOX5 (0.37) ALOX5
SCHEMBL8953837 0.67 ALOX5 (0.35) ALOX5
SCHEMBL8953733 0.67 ALOX5 (0.35) ALOX5
SCHEMBL8953717 0.67
SCHEMBL8953842 0.67 ALOX5 (0.35) ALOX5
SCHEMBL8953852 0.65 HDAC3 (0.32)
SCHEMBL9259112 0.64 ALOX5 (0.43) ALOX5
SCHEMBL8953841 0.64 ACACA (0.41) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5484786-A ANTIALLERGENS, ANTIINFLAMMATORY AGENTS ABBOTT LABORATORIES (US) 1996-01-16 US disclosed