SCHEMBL8956397

SCHEMBL8956397

ClC(Cl)(Cl)c1nc(-c2ccc(C=Cc3ccc(-c4ccccc4)cc3)cc2)nc(C(Cl)(Cl)Cl)n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
KMT2A Q03164 4/20 0.40
CASP3 P42574 2/20 0.40
SENP8 Q96LD8 2/20 0.40
SENP7 Q9BQF6 2/20 0.40
SENP6 Q9GZR1 1/20 0.40
CA1 P00915 1/20 0.40
MGLL Q99685 1/20 0.40
MAPT P10636 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2C19 P33261 1/20 0.37
MEN1 O00255 3/20 0.37
HTT P42858 1/20 0.37
HDAC2 Q92769 2/20 0.37
PTGES O14684 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL699512 0.95 KMT2A (0.44) NPC1RAB9ASMN1; SMN2TDP1L3MBTL1
SCHEMBL274751 0.95 KMT2A (0.44) NPC1RAB9ASMN1; SMN2TDP1L3MBTL1
SCHEMBL125466 0.89 MEN1 (0.44) NPC1RAB9ASMN1; SMN2L3MBTL1KMT2A
SCHEMBL8387126 0.87 ALDH1A1 (0.42) NPC1RAB9ASMN1; SMN2TDP1L3MBTL1
SCHEMBL8387127 0.87 ALDH1A1 (0.42) NPC1RAB9ASMN1; SMN2TDP1L3MBTL1
SCHEMBL80527 0.86 MEN1 (0.47) NPC1RAB9ASMN1; SMN2L3MBTL1KMT2A
SCHEMBL4900598 0.86 MEN1 (0.47) NPC1RAB9ASMN1; SMN2L3MBTL1KMT2A
SCHEMBL8956230 0.85 KDM4E (0.47) NPC1RAB9ASMN1; SMN2TDP1KMT2A
SCHEMBL10226713 0.84 L3MBTL1 (0.47) NPC1RAB9ASMN1; SMN2TDP1L3MBTL1
SCHEMBL3191110 0.84 NFE2L2 (0.48) NPC1RAB9AL3MBTL1KMT2ACASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8400592-B2 Polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2013-03-19 US disclosed
US-8400592-B2 Polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2013-03-19 US disclosed
US-8304025-B2 Optical film, polarizing plate, image display, and manufacturing method of optical film FUJIFILM CORPORATION (JP) 2012-11-06 US disclosed
US-8304025-B2 Optical film, polarizing plate, image display, and manufacturing method of optical film FUJIFILM CORPORATION (JP) 2012-11-06 US disclosed
US-8241740-B2 Layer laminated to support; ionization radiation; curing using free radical catalyst; image display and polarization plates FUJIFILM CORPORATION (JP) 2012-08-14 US disclosed
US-8241740-B2 Layer laminated to support; ionization radiation; curing using free radical catalyst; image display and polarization plates FUJIFILM CORPORATION (JP) 2012-08-14 US disclosed
US-8187704-B2 Optical film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2012-05-29 US disclosed
US-8187704-B2 Optical film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2012-05-29 US disclosed
US-8047662-B2 Antiglare film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2011-11-01 US disclosed
US-8047662-B2 Antiglare film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2011-11-01 US disclosed
US-20080069975-A1 Optical film FUJIFILM CORPORATION (JP) 2008-03-20 US disclosed
US-20070291363-A1 Optical Film FUJIFILM CORPORATION (JP) 2007-12-20 US disclosed
US-20070291363-A1 Optical Film FUJIFILM CORPORATION (JP) 2007-12-20 US disclosed
US-20070243370-A1 Optical film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2007-10-18 US disclosed
US-20070243370-A1 Optical film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2007-10-18 US disclosed
US-20070231566-A1 Optical film, polarizing plate, image display, and manufacturing method of optical film FUJIFILM CORPORATION (JP) 2007-10-04 US disclosed
US-20070231566-A1 Optical film, polarizing plate, image display, and manufacturing method of optical film FUJIFILM CORPORATION (JP) 2007-10-04 US disclosed
WO-2007100143-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2007-09-07 WO disclosed
US-20070104896-A1 Optical film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2007-05-10 US disclosed
US-20070104896-A1 Optical film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2007-05-10 US disclosed