Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9821889 | 0.84 | ALDH1A1 (0.57) | ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8957213 | 0.83 | PTGER4 (0.43) | ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6934282 | 0.81 | HSP90AB1 (0.44) | ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8957045 | 0.81 | ALDH1A1 (0.40) | ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8957202 | 0.76 | PLK1 (0.46) | CYP1A2CYP2C9EGFRGAALMNA | |
| SCHEMBL26296693 | 0.74 | SELL (0.56) | ALDH1A1EGFRGAAMEN1MAPT | |
| SCHEMBL8957203 | 0.73 | ALDH1A1 (0.44) | ALDH1A1EGFRGAAMEN1LMNA | |
| SCHEMBL8878063 | 0.72 | ACHE (0.44) | ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL19182762 | 0.69 | EGFR (0.41) | EGFRGAACXCR2PLK1 | |
| SCHEMBL3365582 | 0.69 | TERT (0.59) | ALDH1A1EGFRGAATAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532383-A | Leukotriene B4 antagonists | G. D. SEARLE & CO. (US) | 1996-07-02 | — | — | US | disclosed |
| EP-0593478-B1 | LEUKOTRIENE B 4 ANTAGONISTS | SEARLE & CO (US) | 1995-12-06 | — | — | EP | disclosed |
| US-5439937-A | Leukotriene B4 antagonists | G. D. SEARLE & CO. (US) | 1995-08-08 | — | — | US | disclosed |
| US-5310951-A | Benzopyran-2-propanoic acid derivatives; antiinflammatory agents | G.D. SEARLE & CO. (US) | 1994-05-10 | — | — | US | disclosed |
| EP-0593478-A1 | LEUKOTRIENE B 4? ANTAGONISTS. | SEARLE & CO (US) | 1994-04-27 | — | — | EP | disclosed |
| US-5124350-A | Antiinflammatory agent | G. D. SEARLE & CO. (US) | 1992-06-23 | — | — | US | disclosed |
| WO-1992000011-A2 | LEUKOTRIENE B4 ANTAGONISTS | G.D. SEARLE & CO. (US) | 1992-01-09 | — | — | WO | disclosed |