Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NNMT | P40261 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8878061 | 0.86 | ACHE (0.44) | ACHEHTR4PARP15PARP10LTB4R | |
| SCHEMBL8957045 | 0.83 | ALDH1A1 (0.40) | PARP15PARP10OPRM1OPRD1OPRK1 | |
| SCHEMBL6935948 | 0.78 | LTB4R (0.44) | LTB4RLTB4R2OPRK1ALDH1A1MEN1 | |
| SCHEMBL8957213 | 0.77 | PTGER4 (0.43) | CYP2C9CYP2C19ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL10690271 | 0.75 | CYP2C9 (0.46) | ACHEHTR4PARP15PARP10CYP2C9 | |
| SCHEMBL27556628 | 0.74 | NNMT (0.44) | PARP10ALDH1A1MAPTTDP1NNMT | |
| SCHEMBL9821889 | 0.74 | ALDH1A1 (0.57) | LTB4RLTB4R2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL7443112 | 0.72 | MEN1 (0.52) | CYP2C9CYP2C19ALDH1A1MEN1KMT2A | |
| SCHEMBL11039311 | 0.72 | NNMT (0.52) | PARP10ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL6934282 | 0.72 | HSP90AB1 (0.44) | CYP2C9CYP2C19ALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684162-A | BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1997-11-04 | — | — | US | disclosed |