Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8958497 | 0.91 | LMNA (0.36) | LMNAGRM5TP53DGAT1XDH | |
| SCHEMBL8872711 | 0.91 | LMNA (0.35) | LMNATP53DGAT1ALDH1A1HTT | |
| SCHEMBL8958444 | 0.88 | WNT3A (0.37) | GRM5XDHWNT3AMAP4K1BCL2 | |
| SCHEMBL8958388 | 0.85 | WNT3A (0.37) | GRM5XDHWNT3AMAP4K1BCL2 | |
| SCHEMBL8873694 | 0.81 | LMNA (0.35) | LMNATP53ALDH1A1MAP4K1HTT | |
| SCHEMBL8876549 | 0.80 | SLC6A3 (0.39) | — | |
| SCHEMBL8958734 | 0.80 | ADORA1 (0.37) | LMNAGRM5TP53DGAT1XDH | |
| SCHEMBL8872200 | 0.79 | ABL1 (0.38) | CYP1A2MAP4K1BCL2MCL1KDM4E | |
| SCHEMBL8872985 | 0.78 | ABL1 (0.37) | GRM5TP53CYP1A2MAP4K1KDM4E | |
| SCHEMBL8949946 | 0.77 | ABL1 (0.39) | CYP1A2MAP4K1KDM4EGSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559236-A | Intermediates for substituted biphenylmethylmidazopyridine angiotensin II antagonists | EISAI CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |