Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 2/20 | 0.48 |
| ▸ | CTSS | P25774 | 5/20 | 0.46 |
| ▸ | CTSL | P07711 | 4/20 | 0.46 |
| ▸ | CTSB | P07858 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.37 |
| ▸ | CTSK | P43235 | 4/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | MTTP | P55157 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8958363 | 0.81 | BDKRB1 (0.46) | BDKRB1ACHECHRNB2CHRNB4CHRNA3 | |
| SCHEMBL8958412 | 0.80 | ACHE (0.41) | BDKRB1ACHECHRNB2CHRNB4CHRNA3 | |
| SCHEMBL5782255 | 0.80 | BDKRB1 (0.66) | BDKRB1ACHE | |
| SCHEMBL8958523 | 0.79 | BDKRB1 (0.49) | BDKRB1CTSSCTSLCTSBACHE | |
| SCHEMBL24736349 | 0.74 | CTSS (0.57) | CTSSCTSLCTSBTLR2CTSK | |
| SCHEMBL8958229 | 0.74 | ACHE (0.51) | BDKRB1ACHECHRNB2CHRNB4CHRNA3 | |
| SCHEMBL5347271 | 0.74 | CTSS (0.57) | CTSSCTSLCTSBTLR2CTSK | |
| SCHEMBL14273893 | 0.73 | HDAC1 (0.51) | BDKRB1CTSSCTSLCTSBCTSK | |
| SCHEMBL15585054 | 0.72 | SYK (0.48) | CTSSCTSLCTSBCTSKSYK | |
| SCHEMBL8234255 | 0.72 | CTSS (0.53) | CTSSCTSLCTSBCTSKMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559233-A | 3-/P-PHENYLBENZYL/IMIDAZOLONES AND PYRIMIDONES | SANOFI (FR) | 1996-09-24 | — | — | US | disclosed |
| US-5352788-A | Angiotensin antagonist | ELF SANOFI (FR) | 1994-10-04 | — | — | US | disclosed |