Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
| ▸ | MTTP | P55157 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PPIB | P23284 | 1/20 | 0.33 |
| ▸ | PPID | Q08752 | 1/20 | 0.33 |
| ▸ | PPIG | Q13427 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BRS3 | P32247 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8958409 | 0.80 | BDKRB1 (0.48) | ACHEBDKRB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL8958363 | 0.80 | BDKRB1 (0.46) | ACHEBDKRB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL8958229 | 0.73 | ACHE (0.51) | ACHEBDKRB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL8958127 | 0.73 | MEN1 (0.40) | ALDH1A1GAAKMT2ANPSR1MAPT | |
| SCHEMBL7352459 | 0.69 | L3MBTL1 (0.41) | NPSR1 | |
| SCHEMBL9030773 | 0.69 | CHRNB2 (0.45) | ACHEBDKRB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL18475231 | 0.68 | ACHE (0.42) | ACHEBDKRB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL5782255 | 0.68 | BDKRB1 (0.66) | ACHEBDKRB1BRS3 | |
| SCHEMBL841128 | 0.68 | PDCD1 (0.53) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL9032066 | 0.68 | GAA (0.48) | ACHEBDKRB1CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559233-A | 3-/P-PHENYLBENZYL/IMIDAZOLONES AND PYRIMIDONES | SANOFI (FR) | 1996-09-24 | — | — | US | disclosed |
| US-5352788-A | Angiotensin antagonist | ELF SANOFI (FR) | 1994-10-04 | — | — | US | disclosed |