SCHEMBL8958899

SCHEMBL8958899

[NH]c1cccc2c1OC(F)(F)C(F)(F)O2

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3146105 0.75 ALDH1A1 (0.33) CETP
SCHEMBL418853 0.75 CETP (0.33) CETP
SCHEMBL3908683 0.75 CETP (0.31) CETP
SCHEMBL7693244 0.75 HTR2C (0.33) CETP
Potassium Ion SCHEMBL13727694 0.72 CETP (0.30) CETP
SCHEMBL848935 0.71 ALOX5 (0.38)
SCHEMBL7266164 0.71 MEN1 (0.38)
SCHEMBL10122079 0.71 GABRA1 (0.38) CETP
SCHEMBL14145511 0.71 CETP (0.39) CETP
SCHEMBL13765704 0.71 CA2 (0.38) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5559253-A Process for the preparation of fluorine-substituted aminobenzodioxles and -benzodioxanes and new intermediates BAYER AKTIENGESELLSCHAFT (DE) 1996-09-24 US disclosed