Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.31 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8976063 | 0.73 | ALDH1A1 (0.37) | ALDH1A1POLBKMT2AELANESRD5A1 | |
| SCHEMBL8958895 | 0.70 | DAO (0.35) | DAOALDH1A1TAAR1ELANEMAPT | |
| SCHEMBL9196655 | 0.70 | ESR1 (0.36) | DAOALDH1A1MEN1KMT2ACYP26A1 | |
| SCHEMBL15173592 | 0.69 | HRH1 (0.34) | DAOALDH1A1TAAR1MEN1KMT2A | |
| SCHEMBL16321921 | 0.68 | POLB (0.33) | POLB | |
| SCHEMBL8781689 | 0.66 | TAAR1 (0.36) | ALDH1A1TAAR1MEN1KMT2ACYP26A1 | |
| SCHEMBL14592601 | 0.65 | GRIN1 (0.38) | ALDH1A1TAAR1POLBMEN1KMT2A | |
| SCHEMBL9331401 | 0.64 | SLC6A3 (0.42) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL2353667 | 0.63 | IDO1 (0.44) | DAOALDH1A1TAAR1MEN1KMT2A | |
| SCHEMBL29003556 | 0.62 | ADAM17 (0.37) | ALDH1A1TAAR1MEN1KMT2AELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2812299-A1 | PROCESS FOR PREPARING CIS-5-[1-(4-CHLOROPHENYL)-METHYLENE]-1-HYDROXYMETHYL-2,2-DIMETHYLCYCLOPENTANOL | BASF Agro B.V., Arnhem (NL), Zürich Branch (CH) | 2014-12-17 | — | — | EP | disclosed |
| WO-2013117629-A1 | PROCESS FOR PREPARING CIS-5-[1-(4-CHLOROPHENYL)-METHYLENE]-1-HYDROXYMETHYL-2,2-DIMETHYLCYCLOPENTANOL | BASF AGRO B.V., ARNHEM (NL), ZÜRICH-BRANCH (CH) | 2013-08-15 | — | — | WO | disclosed |
| WO-2013117629-A1 | PROCESS FOR PREPARING CIS-5-[1-(4-CHLOROPHENYL)-METHYLENE]-1-HYDROXYMETHYL-2,2-DIMETHYLCYCLOPENTANOL | BASF AGRO B.V., ARNHEM (NL), ZÜRICH-BRANCH (CH) | 2013-08-15 | — | — | WO | disclosed |
| US-20130184470-A1 | Process for preparing 5-[1-(4-chlorophenyl)-methylene]-1-hydroxymethyl-2,2-dimethyl-cyclopentanol | BASF SE (DE) | 2013-07-18 | — | — | US | disclosed |
| US-20130184470-A1 | Process for preparing 5-[1-(4-chlorophenyl)-methylene]-1-hydroxymethyl-2,2-dimethyl-cyclopentanol | BASF SE (DE) | 2013-07-18 | — | — | US | disclosed |
| EP-0474303-B1 | Process for the preparation of cyclopentane derivatives and intermediates therefor | SHELL INT RESEARCH (NL) | 1996-01-17 | — | — | EP | disclosed |
| EP-0474301-B1 | Cyclohexanone derivatives | SHELL INT RESEARCH (NL) | 1995-12-20 | — | — | EP | disclosed |
| US-5200535-A | Intermediates for fungicides | SHELL RESEARCH LIMITED (GB) | 1993-04-06 | — | — | US | disclosed |
| US-5151550-A | Cyclopentane derivatives | SHELL RESEARCH LIMITED (GB) | 1992-09-29 | — | — | US | disclosed |
| EP-0474301-A2 | Cyclohexanone derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-03-11 | — | — | EP | disclosed |
| EP-0474303-A1 | Process for the preparation of cyclopentane derivatives and intermediates therefor | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-03-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130184470-A1 | Process for preparing 5-[1-(4-chlorophenyl)-methylene]-1-hydroxymethyl-2,2-dimethyl-cyclopentanol | CYP2E1, DHPS, CYP1B1 | DAO 525/4885ALDH1A1 105/4885RXRA 4309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.