Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8976520 | 0.82 | PTGS1 (0.35) | ALDH1A1PTGS1PTGS2POLBALPL | |
| SCHEMBL8996595 | 0.82 | SMN1; SMN2 (0.40) | ALDH1A1PTGS2NPC1RAB9A | |
| SCHEMBL20721293 | 0.75 | EEF2K (0.34) | — | |
| SCHEMBL8959059 | 0.73 | DAO (0.40) | ALDH1A1POLBELANESRD5A1KMT2A | |
| SCHEMBL16321921 | 0.72 | POLB (0.33) | POLB | |
| SCHEMBL1567626 | 0.67 | SIGMAR1 (0.43) | RECQLPTGS1PTGS2ALPLSIGMAR1 | |
| SCHEMBL16322256 | 0.66 | CYP19A1 (0.33) | — | |
| SCHEMBL959235 | 0.66 | CYP19A1 (0.33) | — | |
| SCHEMBL28756264 | 0.66 | MT-CO2 (0.53) | ALDH1A1PTGS1PTGS2SIGMAR1 | |
| SCHEMBL4329065 | 0.65 | CYP19A1 (0.32) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571831-A | FUNGICIDE, AROMATASE INHIBITOR, ANTITUMOR | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| US-5547973-A | AZOLE MODIFIED CYCLOHEXANOL; ANTITUMOR AGENT | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-08-20 | — | — | US | disclosed |
| US-5508298-A | ADMINISTERING AS ANTITUMOR AGENT | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-04-16 | — | — | US | disclosed |
| US-5489597-A | 2,2-DIMETHYL-5-HALOPHENYL-1-(1H,-1,2,4-TRIAZOLE-1-YLMETHYL) -CYCLOHEXANE-1-OL OR A SALT THEREOF FUNGICIDES | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-02-06 | — | — | US | disclosed |
| EP-0621268-A1 | NOVEL AZOLE DERIVATIVE, PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITION | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-10-26 | — | — | EP | disclosed |