SCHEMBL8959129

SCHEMBL8959129

CC(C)Oc1ccc(OCCNC(=O)C2CC2)c(Cl)c1

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.49
MEN1 O00255 3/20 0.49
ABL1 P00519 1/20 0.46
PKM P14618 2/20 0.45
NPC1 O15118 1/20 0.45
EPHX2 P34913 1/20 0.45
RAB9A P51151 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
PPARD Q03181 1/20 0.45
PPARA Q07869 1/20 0.45
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
MTNR1A P48039 3/20 0.42
MTNR1B P49286 3/20 0.42
FFAR4 Q5NUL3 1/20 0.42
ACACB O00763 2/20 0.42
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8959018 0.90 KMT2A (0.48) KMT2AMEN1ABL1PKMNPC1
SCHEMBL8959189 0.83 PKM (0.56) KMT2AMEN1ABL1PKMNPC1
SCHEMBL8959066 0.82 KMT2A (0.53) KMT2AMEN1ABL1PKMNPC1
SCHEMBL8959167 0.81 KMT2A (0.50) KMT2AMEN1ABL1PKMNPC1
SCHEMBL8959169 0.81 NPC1 (0.52) KMT2AMEN1ABL1PKMNPC1
SCHEMBL8959049 0.81 PPARA (0.45) KMT2AMEN1ABL1PKMNPC1
SCHEMBL8959068 0.81 ABL1 (0.53) KMT2AMEN1ABL1PKMNPC1
SCHEMBL8958875 0.79 MEN1 (0.50) KMT2AMEN1PKMNPC1EPHX2
SCHEMBL8959191 0.79 NPC1 (0.45) KMT2AMEN1ABL1PKMNPC1
SCHEMBL8958993 0.79 ABL1 (0.51) KMT2AMEN1ABL1PKMNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0514833-B1 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL CO (JP) 1996-01-17 EP disclosed
US-5364966-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-11-15 US disclosed
US-5356930-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-10-18 US disclosed
EP-0514833-A2 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-11-25 EP disclosed