SCHEMBL8959191

SCHEMBL8959191

O=C(NCCOc1ccc(Oc2ccc(F)cc2F)cc1Cl)C1CC1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.45
RAB9A P51151 3/20 0.45
ALDH1A1 P00352 2/20 0.45
LMNA P02545 1/20 0.45
PPARA Q07869 6/20 0.44
PPARD Q03181 4/20 0.44
KMT2A Q03164 3/20 0.43
PPARG P37231 3/20 0.43
MEN1 O00255 2/20 0.43
PKM P14618 2/20 0.43
PTGDR2 Q9Y5Y4 1/20 0.42
KDR P35968 4/20 0.42
BRAF P15056 3/20 0.42
ABL1 P00519 1/20 0.41
EPHX2 P34913 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8958993 0.88 ABL1 (0.51) NPC1RAB9AALDH1A1LMNAPPARA
SCHEMBL8959049 0.87 PPARA (0.45) NPC1RAB9AALDH1A1LMNAPPARA
SCHEMBL8959169 0.83 NPC1 (0.52) NPC1RAB9AALDH1A1KMT2AMEN1
SCHEMBL8959189 0.83 PKM (0.56) NPC1RAB9APPARAPPARDKMT2A
SCHEMBL9161292 0.81 PPARA (0.46) NPC1RAB9AALDH1A1PPARAPPARD
SCHEMBL8958875 0.81 MEN1 (0.50) NPC1RAB9ALMNAPPARAPPARD
SCHEMBL8959068 0.81 ABL1 (0.53) NPC1RAB9AALDH1A1PPARAPPARD
SCHEMBL8958936 0.79 NPC1 (0.43) NPC1RAB9AALDH1A1LMNAKMT2A
SCHEMBL8959129 0.79 KMT2A (0.49) NPC1RAB9AALDH1A1LMNAPPARA
SCHEMBL8959167 0.79 KMT2A (0.50) NPC1RAB9AALDH1A1PPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0514833-B1 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL CO (JP) 1996-01-17 EP disclosed
US-5364966-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-11-15 US disclosed
US-5356930-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-10-18 US disclosed
EP-0514833-A2 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-11-25 EP disclosed