SCHEMBL8959907

SCHEMBL8959907

CCCCN(C(=O)c1ccc(O)cc1)c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.64
ADRB2 P07550 1/20 0.64
MAPT P10636 2/20 0.61
ADRA2C P18825 1/20 0.59
ESR1 P03372 2/20 0.52
GAA P10253 3/20 0.51
HPGD P15428 2/20 0.51
NPC1 O15118 1/20 0.51
JAK2 O60674 1/20 0.51
RAB9A P51151 1/20 0.51
PAX8 Q06710 1/20 0.51
LTB4R2 Q9NPC1 1/20 0.51
HDAC1 Q13547 1/20 0.51
HDAC6 Q9UBN7 1/20 0.51
ESR2 Q92731 1/20 0.49
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2C9 P11712 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9001628 0.91 ADRA2C (0.71) ALDH1A1ADRB2MAPTADRA2CGAA
SCHEMBL11506841 0.87 ALDH1A1 (0.63) ALDH1A1ADRB2MAPTADRA2CGAA
SCHEMBL15291404 0.84 ADRA2C (0.67) ALDH1A1ADRB2MAPTADRA2CGAA
SCHEMBL11506563 0.81 ADRA2C (0.58) ALDH1A1ADRB2MAPTADRA2CGAA
SCHEMBL9001626 0.80 ADRA2C (0.65) ALDH1A1ADRB2MAPTADRA2CHPGD
SCHEMBL10964238 0.79 ALDH1A1 (0.66) ALDH1A1ADRB2MAPTADRA2CESR1
SCHEMBL2892022 0.79 NPC1 (0.61) ALDH1A1ADRB2MAPTADRA2CESR1
SCHEMBL1928093 0.78 PKM (0.54) ALDH1A1ADRB2MAPTADRA2CHPGD
SCHEMBL9716677 0.78 ADRA2C (0.53) ALDH1A1MAPTADRA2CESR1HPGD
SCHEMBL6323267 0.77 ALDH1A1 (0.59) ALDH1A1ADRB2MAPTADRA2CGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544908-B1 THERMOPLASTIC ELASTOMER COMPOSITION SUMITOMO CHEMICAL CO (JP) 1996-01-31 EP disclosed