Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8959557 | 0.79 | HTR2A (0.48) | ICMT | |
| SCHEMBL8959753 | 0.79 | HTR2A (0.48) | ICMT | |
| SCHEMBL8959883 | 0.79 | TRPM5 (0.31) | — | |
| SCHEMBL8959843 | 0.79 | ICMT (0.36) | ICMT | |
| SCHEMBL8959696 | 0.75 | AR (0.34) | — | |
| SCHEMBL27447136 | 0.75 | AR (0.34) | — | |
| Fumaric Acid SCHEMBL8959914 | 0.72 | HTR2A (0.47) | ICMT | |
| Fumaric Acid SCHEMBL8959900 | 0.72 | HTR2A (0.47) | ICMT | |
| Fumaric Acid SCHEMBL27340852 | 0.72 | HTR2A (0.47) | ICMT | |
| SCHEMBL8959949 | 0.71 | SLC22A12 (0.35) | ICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1061341-C | 1-amino-ethylindole-derivatives | HOFFMANN LA ROCHE (CH) | 2001-01-31 | — | — | CN | disclosed |
| US-5494928-A | FOR CENTRAL NERVOUS SYSTEM DISORDERS, BLOCKING SEROTONIN RECEPTORS, ANTIDEPRESSANTS | HOFFMANN-LA ROCHE INC. (US) | 1996-02-27 | — | — | US | disclosed |
| CN-1105988-A | 1-amino-ethylindole-derivatives | HOFFMANN LA ROCHE (CH) | 1995-08-02 | — | — | CN | disclosed |