Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8959667 | 0.83 | TRPM5 (0.38) | TRPM5 | |
| SCHEMBL8959909 | 0.79 | ICMT (0.32) | — | |
| Fumaric Acid SCHEMBL8959880 | 0.73 | HTR2C (0.36) | — | |
| Fumaric Acid SCHEMBL8959888 | 0.73 | HTR2C (0.36) | — | |
| SCHEMBL8959747 | 0.73 | AR (0.44) | — | |
| SCHEMBL8959557 | 0.70 | HTR2A (0.48) | — | |
| SCHEMBL8959753 | 0.70 | HTR2A (0.48) | — | |
| SCHEMBL8959643 | 0.70 | AR (0.33) | — | |
| SCHEMBL7994539 | 0.70 | ALDH1A1 (0.38) | — | |
| SCHEMBL8959659 | 0.69 | ICMT (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494928-A | FOR CENTRAL NERVOUS SYSTEM DISORDERS, BLOCKING SEROTONIN RECEPTORS, ANTIDEPRESSANTS | HOFFMANN-LA ROCHE INC. (US) | 1996-02-27 | — | — | US | disclosed |