SCHEMBL8960098

SCHEMBL8960098

C#CCOc1cc(-n2cnc(C(F)(F)F)cc2=O)c(F)cc1[N+](=O)[O-]

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8960224 0.84 TDP1 (0.37) POLBMAPTPKM
SCHEMBL8960296 0.83 ALDH1A1 (0.31) MAPT
SCHEMBL8960336 0.82 POLB (0.33) POLBMAPTPKM
SCHEMBL8960188 0.79 HCAR1 (0.36) POLBMAPTPKM
SCHEMBL11785278 0.73 HCAR1 (0.53) POLBMAPTPKM
SCHEMBL9343857 0.69 TDP1 (0.41) POLBMAPT
SCHEMBL9343938 0.67 TDP1 (0.45) POLBMAPT
SCHEMBL7085889 0.67 TRPV4 (0.37)
SCHEMBL8960424 0.66 PPOX (0.33) POLB
SCHEMBL25027181 0.66 POLB (0.43) POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5532208-A HERBICIDES SUMITOMO CHEMICAL CO., LTD. (JP) 1996-07-02 US disclosed
US-5366955-A HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-11-22 US disclosed
EP-0568041-A1 Pyrimidone derivatives and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-11-03 EP disclosed