Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | BCAT2 | O15382 | 6/20 | 0.34 |
| ▸ | BCAT1 | P54687 | 6/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ALPI | P09923 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3480560 | 0.81 | CYP11B2 (0.38) | TRPV4ESR2CYP11B1CYP11B2KDM1A | |
| SCHEMBL8505383 | 0.80 | PGR (0.37) | SCN9A | |
| SCHEMBL9581996 | 0.78 | HCAR1 (0.40) | ESR2SCN9A | |
| SCHEMBL9581479 | 0.77 | ESR2 (0.32) | KDM5BALPLALPIESR2CYP11B1 | |
| SCHEMBL9730727 | 0.76 | KDM5B (0.35) | KDM5BALPLALPIESR2ALDH1A1 | |
| SCHEMBL7698169 | 0.75 | TRPV4 (0.38) | TRPV4BCAT2BCAT1CYP11B1CYP11B2 | |
| SCHEMBL9581461 | 0.73 | ALPI (0.34) | TRPV4ALPIESR2 | |
| SCHEMBL9765847 | 0.73 | GAA (0.39) | KDM5BALPLALPIESR2CYP11B1 | |
| SCHEMBL8193399 | 0.72 | ALPL (0.39) | BCAT2BCAT1ALPLALPICYP11B1 | |
| SCHEMBL7694103 | 0.72 | MEN1 (0.40) | TRPV4BCAT2BCAT1ALPLALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1030846-B1 | METHOD FOR PRODUCING AR(ALK)YLURACILES, NOVEL CORRESPONDING INTERMEDIATE PRODUCTS AND METHOD FOR PRODUCING SAID INTERMEDIATE PRODUCTS | BAYER CROPSCIENCE AG (DE) | 2003-07-16 | — | — | EP | disclosed |
| US-6476224-B2 | N-(4-CYANO-2,5- DIFLUORO-PHENYL) -3-(DIMETHYLAMINOCARBONYLAMINO)-4,4,4-TRIFLUORO-2-BUTENAMIDE AND 1,2-DIMETHOXYETHANE ARE HEATED TO FORM AR(ALK)YL URACIL COMPOUND | BAYER AKTIENGESELLSCHAFT (DE) | 2002-11-05 | — | — | US | disclosed |
| US-20020022727-A1 | Method for producing ar(alk)yluraciles, novel corresponding intermediate products and method for producing said intermediate products | GALLENKAMP BERND (DE) | 2002-02-21 | — | — | US | disclosed |
| US-6262291-B1 | CHEMICAL INTERMEDIATE FOR HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-17 | — | — | US | disclosed |
| US-6225470-B1 | HEATING SUBSTITUTED AMINOALKENAMIDES IN PRESENCE OF DILUENTS TO PRODUCE AR(ALK)YLURACIL | BAYER AKTIENGESELLSCHAFT (DE) | 2001-05-01 | — | — | US | disclosed |
| US-6169182-B1 | REACTING SUBSTITUTED N-(CYANOPHENYL)AMINOALKENAMIDES WITH CARBONIC ACID DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-02 | — | — | US | disclosed |
| EP-1030846-A1 | METHOD FOR PRODUCING AR(ALK)YLURACILES, NOVEL CORRESPONDING INTERMEDIATE PRODUCTS AND METHOD FOR PRODUCING SAID INTERMEDIATE PRODUCTS | BAYER AG (DE) | 2000-08-30 | — | — | EP | disclosed |
| WO-1999025698-A1 | METHOD FOR PRODUCING AR(ALK)YLURACILES, NOVEL CORRESPONDING INTERMEDIATE PRODUCTS AND METHOD FOR PRODUCING SAID INTERMEDIATE PRODUCTS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-05-27 | — | — | WO | disclosed |
| US-5877121-A | HERBICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1999-03-02 | — | — | US | disclosed |
| EP-0880506-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED CYANOPHENYL URACILS FROM SUBSTITUTED AMINOALKENE ACID CYANOPHENYL AMIDES | BAYER AG (DE) | 1998-12-02 | — | — | EP | disclosed |
| EP-0804424-A1 | SUBSTITUTED PYRIMIDINE(THI)ONES | BAYER AG (DE) | 1997-11-05 | — | — | EP | disclosed |
| WO-1997029094-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED CYANOPHENYL URACILS FROM SUBSTITUTED AMINOALKENE ACID CYANOPHENYL AMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-08-14 | — | — | WO | disclosed |
| WO-1996007647-A1 | SUBSTITUTED PYRIMIDINE(THI)ONES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-03-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020022727-A1 | Method for producing ar(alk)yluraciles, novel corresponding intermediate products and method for producing said intermediate products | ALK, ALKBH5, ALKBH1 | TRPV4 3652/4885BCAT2 796/4885BCAT1 895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.