Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 6/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9444232 | 0.75 | ACHE (0.65) | PLA2G2AEPHX1EPHX2ACHENPC1 | |
| SCHEMBL8576882 | 0.75 | ACHE (0.65) | PLA2G2AEPHX1EPHX2ACHENPC1 | |
| SCHEMBL8913848 | 0.75 | ACHE (0.65) | PLA2G2AEPHX1EPHX2ACHENPC1 | |
| SCHEMBL8849277 | 0.73 | ACHE (0.61) | EPHX1EPHX2ACHENPC1RAB9A | |
| SCHEMBL11172758 | 0.72 | PLA2G2A (0.49) | PLA2G2AEPHX1EPHX2ACHEFAAH | |
| SCHEMBL7166158 | 0.72 | ALDH1A1 (0.42) | PLA2G2AEPHX1ACHENAAAHCAR2 | |
| SCHEMBL8960640 | 0.70 | ACHE (0.57) | EPHX1EPHX2ACHEFAAHNPC1 | |
| SCHEMBL8960621 | 0.70 | ACHE (0.57) | EPHX1EPHX2ACHEFAAHNPC1 | |
| SCHEMBL8960685 | 0.70 | ACHE (0.57) | EPHX1EPHX2ACHEFAAHNPC1 | |
| SCHEMBL5258058 | 0.68 | FAAH (0.57) | PLA2G2AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0498729-B1 | Dipeptide derivatives with urethan groupings, their preparation and their application, especially as hydratating agents and tensioactive agents in cosmetic, pharmaceutical and alimentary preparations | OREAL (FR) | 1996-01-31 | — | — | EP | claimed |
| EP-0498729-A1 | Dipeptide derivatives with urethan groupings, their preparation and their application, especially as hydratating agents and tensioactive agents in cosmetic, pharmaceutical and alimentary preparations | L'OREAL (FR) | 1992-08-12 | — | — | EP | claimed |
| EP-0498729-B1 | Dipeptide derivatives with urethan groupings, their preparation and their application, especially as hydratating agents and tensioactive agents in cosmetic, pharmaceutical and alimentary preparations | OREAL (FR) | 1996-01-31 | — | — | EP | disclosed |
| EP-0498729-A1 | Dipeptide derivatives with urethan groupings, their preparation and their application, especially as hydratating agents and tensioactive agents in cosmetic, pharmaceutical and alimentary preparations | L'OREAL (FR) | 1992-08-12 | — | — | EP | disclosed |