Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | PNP | P00491 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | OGA | O60502 | 1/20 | 0.33 |
| ▸ | TK1 | P04183 | 2/20 | 0.31 |
| ▸ | TK2 | O00142 | 1/20 | 0.31 |
| ▸ | POLA1 | P09884 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8698135 | 0.96 | DNMT1 (0.35) | DNMT1LMNASMN1; SMN2ADRB1PNP | |
| SCHEMBL8927785 | 0.78 | DNMT1 (0.39) | DNMT1LMNASMN1; SMN2ADRB1PNP | |
| SCHEMBL8927834 | 0.77 | LMNA (0.38) | DNMT1LMNASMN1; SMN2ADRB1OGA | |
| SCHEMBL7661689 | 0.72 | LMNA (0.38) | DNMT1LMNASMN1; SMN2ADRB1PNP | |
| SCHEMBL18190788 | 0.72 | DNMT1 (0.39) | DNMT1LMNASMN1; SMN2ADRB1PNP | |
| SCHEMBL9633782 | 0.71 | LMNA (0.37) | DNMT1LMNASMN1; SMN2ADRB1OGA | |
| SCHEMBL9634749 | 0.71 | LMNA (0.37) | DNMT1LMNASMN1; SMN2ADRB1OGA | |
| SCHEMBL16631956 | 0.66 | TK1 (0.37) | DNMT1LMNASMN1; SMN2ADRB1TK1 | |
| SCHEMBL9751247 | 0.65 | ADRB1 (0.38) | DNMT1LMNASMN1; SMN2ADRB1OGA | |
| SCHEMBL8663124 | 0.65 | ADRB1 (0.38) | DNMT1LMNASMN1; SMN2ADRB1OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5525711-A | MONOMERS FOR DNA AMPLIFICATION PROCEDURES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1996-06-11 | — | — | US | disclosed |