Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propene SCHEMBL11695388 | 0.88 | RAPGEF4 (0.32) | RAPGEF4MEN1KMT2ATP53TDP1 | |
| SCHEMBL6353240 | 0.78 | CYP3A4 (0.46) | MEN1KMT2AALDH1A1GAAACHE | |
| SCHEMBL12705758 | 0.76 | POLB (0.46) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL9935610 | 0.75 | RAPGEF4 (0.43) | RAPGEF4MEN1KMT2AALDH1A1KDM4E | |
| Dimesityl Disulfide SCHEMBL896126 | 0.75 | RAPGEF4 (0.43) | RAPGEF4MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL758797 | 0.73 | RAPGEF4 (0.41) | RAPGEF4MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL24915470 | 0.71 | RAPGEF4 (0.39) | RAPGEF4MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL21415458 | 0.71 | RAPGEF4 (0.39) | RAPGEF4MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL22368224 | 0.71 | RAPGEF4 (0.39) | RAPGEF4MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL15268372 | 0.71 | RAPGEF4 (0.39) | RAPGEF4MEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120083627-A1 | Method of Synthesis of Arylsulfur Trifluorides and Use as in situ Deoxofluorination Reagent | FLUOROTECH, LLC (US) | 2012-04-05 | — | — | US | claimed |
| US-20070270542-A1 | Crosslinkable Polymer Systems | REICHHOLD, INC. | 2007-11-22 | — | — | US | disclosed |
| WO-2006083338-A1 | FUNCTIONALIZED THERMOSETTING RESIN SYSTEMS | REICHHOLD, INC. (US) | 2006-08-10 | — | — | WO | disclosed |
| US-20060173142-A1 | Functionalized thermosetting resin systems | REICHHOLD, INC. | 2006-08-03 | — | — | US | disclosed |
| WO-2006041553-A1 | CROSSLINKABLE POLYMER SYSTEMS | REICHHOLD, INC. (US) | 2006-04-20 | — | — | WO | disclosed |
| US-20060079624-A1 | Crosslinkable polymer systems | REICHHOLD, INC. | 2006-04-13 | — | — | US | disclosed |
| US-6900307-B1 | 2-aminopurine derivatives | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 2005-05-31 | — | — | US | disclosed |
| EP-1363959-A1 | MAKING POLYOLEFIN GRAFT COPOLYMERS WITH LOW MOLECULAR WEIGHT SIDE CHAINS USING A POLYMERIC PEROXIDE AS AN INITIATOR | Basell Poliolefine Italia S.p.A. (IT) | 2003-11-26 | — | — | EP | disclosed |
| EP-1330478-A1 | IRRADIATION PROCESS FOR MAKING OLEFIN GRAFT COPOLYMERS WITH LOW MOLECULAR WEIGHT SIDE CHAINS | Basell Poliolefine Italia S.p.A. (IT) | 2003-07-30 | — | — | EP | disclosed |
| US-6518327-B1 | Graft copolymers were made from a propylene homopolymer to which was graft polymerized polystyrene or poly(methyl methacylate) in the prsence of a hydroxylamine polymerization inhibitor | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2003-02-11 | — | — | US | disclosed |
| EP-1236736-A1 | 2-AMINOPURINE DERIVATIVES | HISAMITSU PHARMACEUTICAL CO. INC. (JP) | 2002-09-04 | — | — | EP | disclosed |
| US-6444722-B1 | PROCESS CONTROL | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2002-09-03 | — | — | US | disclosed |
| WO-2002036650-A1 | IRRADIATION PROCESS FOR MAKING OLEFIN GRAFT COPOLYMERS WITH LOW MOLECULAR WEIGHT SIDE CHAINS | BASELL TECHNOLOGY COMPANY B.V. (US) | 2002-05-10 | — | — | WO | disclosed |
| WO-2002036649-A1 | MAKING POLYOLEFIN GRAFT COPOLYMERS WITH LOW MOLECULAR WEIGHT SIDE CHAINS USING A POLYMERIC PEROXIDE AS AN INITIATOR | BASELL TECHNOLOGY COMPANY B.V. (US) | 2002-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120083627-A1 | Method of Synthesis of Arylsulfur Trifluorides and Use as in situ Deoxofluorination Reagent | AFF2, BRD2, AFF4 | RAPGEF4 3158/4885MEN1 4486/4885KMT2A 3682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.