Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7692955 | 0.91 | MEN1 (0.87) | MEN1KMT2AMAPTALOX5CYP3A4 | |
| SCHEMBL875812 | 0.85 | MEN1 (1.00) | MEN1KMT2AMAPTALOX5CYP3A4 | |
| SCHEMBL574272 | 0.85 | MEN1 (0.62) | MEN1KMT2AMAPTALOX5CYP3A4 | |
| SCHEMBL29655583 | 0.82 | ALOX5 (1.00) | MEN1KMT2AMAPTALOX5CYP3A4 | |
| SCHEMBL29655585 | 0.82 | ALOX5 (1.00) | MEN1KMT2AMAPTALOX5CYP3A4 | |
| SCHEMBL68292 | 0.82 | ALOX5 (1.00) | MEN1KMT2AMAPTALOX5CYP3A4 | |
| Clorophene SCHEMBL9761818 | 0.78 | MEN1 (0.79) | MEN1KMT2AMAPTALOX5CYP3A4 | |
| SCHEMBL11260186 | 0.77 | MEN1 (0.65) | MEN1KMT2AMAPTCYP3A4HPGD | |
| SCHEMBL6916752 | 0.77 | ALOX5 (0.75) | MEN1KMT2AMAPTALOX5CYP3A4 | |
| SCHEMBL4055779 | 0.76 | MAPT (0.81) | MEN1KMT2AMAPTALOX5CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693919-A1 | ORAL COMPOSITIONS FOR TREATING PLAQUE AND GINGIVITIS CONTAINING A NONCATIONIC ANTIBACTERIAL AGENT AND A BICARBONATE SALT | THE PROCTER & GAMBLE COMPANY (US) | 1996-01-31 | — | — | EP | disclosed |
| EP-0676948-A1 | ANTIPLAQUE, ANTIGINGIVITIS, ANTICARIES ORAL COMPOSITION | Colgate-Palmolive Company (US) | 1995-10-18 | — | — | EP | disclosed |
| WO-1994023691-A2 | ORAL COMPOSITIONS FOR TREATING PLAQUE AND GINGIVITIS CONTAINING A NONCATIONIC ANTIBACTERIAL AGENT AND A BICARBONATE SALT | THE PROCTER & GAMBLE COMPANY (US) | 1994-10-27 | — | — | WO | disclosed |
| WO-1994013254-A1 | ANTIPLAQUE, ANTIGINGIVITIS, ANTICARIES ORAL COMPOSITION | COLGATE-PALMOLIVE COMPANY (US) | 1994-06-23 | — | — | WO | disclosed |