Water

Water

SCHEMBL8961675

O.O.O.O=[N+]([O-])[O-].O=[N+]([O-])[O-].[Mg+2]

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 known ✓ O00255 1/20 0.67
KMT2A Q03164 1/20 0.67
CA5A P35218 1/20 0.46
CA5B Q9Y2D0 1/20 0.46
TSHR P16473 3/20 0.39
ALDH1A1 P00352 3/20 0.39
TDP1 Q9NUW8 1/20 0.39
HPGD P15428 1/20 0.36
HIF1A Q16665 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL219368 1.00 MEN1 (0.67) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL6346899 1.00 MEN1 (0.67) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL6221351 1.00 MEN1 (0.67) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL28315089 1.00 MEN1 (0.67) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL94658 1.00 MEN1 (0.67) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL6038352 1.00 MEN1 (0.67) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL16334813 1.00 MEN1 (0.67) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL4176811 1.00 MEN1 (0.67) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL1982246 1.00 MEN1 (0.67) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL9755739 1.00 MEN1 (0.67) MEN1KMT2ACA5ACA5BTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119326908-A Palladium nanocluster/hydrotalcite nanocomposite and preparation method and application thereof 中国科学院理化技术研究所 2025-01-21 CN claimed
CN-113731135-B Carbon dioxide trapping agent for preparing fertilizer from amino acid waste liquid 北京锦绣新技术发展有限公司 2022-02-11 CN claimed
CN-113731135-A Carbon dioxide trapping agent for preparing fertilizer from amino acid waste liquid 北京锦绣新技术发展有限公司 2021-12-03 CN claimed
CN-105883869-A Method for producing magnesium nitrate lower hydrate from boron mud waste material 常德云港生物科技有限公司 2016-08-24 CN claimed
CN-102219241-A Method for preparing magnesium nitrate low-hydrate and co-producing calcium hydroxide and manganese hydroxide by using boric sludge JIAXING WANG 2011-10-19 CN claimed
US-5302763-A Reacting toluene with nitric acid in presence of hydrated nitrate salts to reduce hazard of detonation OLIN CORPORATION (US) 1994-04-12 US claimed
US-5099079-A PROCESS FOR SEPARATING ACID FROM NITRO SUBSTITUTED AROMATICS USING A MOLTEN NITRATE SALT OLIN CORPORATION (US) 1992-03-24 US claimed
WO-1992001666-A1 A PROCESS FOR SEPARATING ACID FROM NITRO SUBSTITUTED AROMATICS USING A MOLTEN NITRATE SALT OLIN CORPORATION (US) 1992-02-06 WO claimed
WO-1991011429-A1 PROCESS FOR PURIFYING AROMATIC NITRATION PRODUCTS OLIN CORPORATION (US) 1991-08-08 WO claimed
US-5012019-A Process for purifying aromatic nitration products OLIN CORPORATION (US) 1991-04-30 US claimed
CN-119326908-A Palladium nanocluster/hydrotalcite nanocomposite and preparation method and application thereof 中国科学院理化技术研究所 2025-01-21 CN disclosed
CN-113731135-B Carbon dioxide trapping agent for preparing fertilizer from amino acid waste liquid 北京锦绣新技术发展有限公司 2022-02-11 CN disclosed
CN-113731135-A Carbon dioxide trapping agent for preparing fertilizer from amino acid waste liquid 北京锦绣新技术发展有限公司 2021-12-03 CN disclosed
CN-107597108-B A kind of naphthane adds hydrogen to prepare catalyst of decahydronaphthalene and its preparation method and application 西南化工研究设计院有限公司 2019-10-18 CN disclosed
CN-105190854-B Coating liquid for forming metal oxide film, field effect transistor, and method for manufacturing field effect transistor 株式会社理光 2018-01-30 CN disclosed
US-4918250-A Process for the production of dinitrotoluene using an inorganic salt as a phase separation agent OLIN CORPORATION (US) 1990-04-17 US disclosed
US-4238317-A Catalytic cracking with reduced emission of noxious gases STANDARD OIL COMPANY (INDIANA) (US) 1980-12-09 US disclosed
US-4221677-A MIXTURE OF ZEOLITE, METALLIC OXIDE REACTANT FOR DESULFURIZATION AND GROUP 8 METAL OR RHENIUM OXIDATION PROMOTER STANDARD OIL COMPANY (INDIANA) (US) 1980-09-09 US disclosed
US-4153535-A CYCLIC FLUIDIZED PROCESS USING PROMOTED MOLECULAR SIEVE TO DESULFURIZE STANDARD OIL COMPANY (INDIANA) (US) 1979-05-08 US disclosed
US-4146463-A BY REACTION WITH METAL OXIDES, COMBUSTION STANDARD OIL COMPANY (INDIANA) (US) 1979-03-27 US disclosed