Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TNFSF10 | P50591 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1245257 | 0.86 | NPC1 (0.47) | NPC1RAB9ACYP1A2LMNAMAPT | |
| SCHEMBL29354045 | 0.86 | NPC1 (0.47) | NPC1RAB9ACYP1A2LMNAMAPT | |
| SCHEMBL16019276 | 0.80 | NPC1 (0.44) | NPC1RAB9ACYP1A2LMNAMAPT | |
| SCHEMBL1245251 | 0.77 | NPC1 (0.41) | MAPK1NPC1RAB9ACYP1A2LMNA | |
| SCHEMBL22207363 | 0.77 | TP53 (0.45) | NPC1RAB9ACYP1A2LMNAMAPT | |
| SCHEMBL6842063 | 0.77 | NPC1 (0.41) | MAPK1NPC1RAB9ACYP1A2LMNA | |
| SCHEMBL15894216 | 0.77 | RAB9A (0.49) | MAPK1NPC1RAB9ACYP1A2LMNA | |
| SCHEMBL22207162 | 0.77 | RAB9A (0.47) | HSP90AA1HSP90AB1NPC1RAB9AHTT | |
| SCHEMBL19901679 | 0.77 | NPC1 (0.49) | MAPK1NPC1RAB9ACYP1A2MAPT | |
| SCHEMBL29974237 | 0.77 | NPC1 (0.41) | MAPK1NPC1RAB9ACYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0395938-B1 | Process for the preparation of 2-(2',4'-dihydroxyphenyl)-4,6-diaryl-s-triazines | CIBA GEIGY AG (CH) | 1996-01-17 | — | — | EP | disclosed |
| US-5106972-A | 2-METHYL-THIO-4,6-DIARYL-TRIAZINES | CIBA-GEIGY CORPORATION (US) | 1992-04-21 | — | — | US | disclosed |
| US-5084570-A | PROCESS FOR THE PREPARATION OF 2-(2',4'-DIHYDROXYPHENYL)-4,6-DIARYL-S-TRIAZINES | CIBA-GEIGY CORPORATION (US) | 1992-01-28 | — | — | US | disclosed |
| EP-0395938-A2 | Process for the preparation of 2-(2',4'-dihydroxyphenyl)-4,6-diaryl-s-triazines | CIBA-GEIGY AG (CH) | 1990-11-07 | — | — | EP | disclosed |