Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | FABP3 | P05413 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962989 | 0.89 | KMT2A (0.48) | SRC | |
| SCHEMBL8962444 | 0.84 | SOAT2 (0.41) | FABP3FABP4FABP5TDP1SOAT2 | |
| SCHEMBL5188630 | 0.76 | ALDH1A1 (0.54) | FABP3FABP4FABP5KAT6AGAA | |
| SCHEMBL8962533 | 0.76 | KMT2A (0.43) | SOAT1 | |
| SCHEMBL8720137 | 0.72 | FABP4 (0.58) | FABP3FABP4FABP5TDP1SOAT2 | |
| SCHEMBL8962404 | 0.71 | FABP3 (0.46) | FABP3FABP4FABP5SOAT2MYC | |
| SCHEMBL6480534 | 0.69 | SRC (0.56) | SRCPTPN1PTPN6PTPN11TDP1 | |
| SCHEMBL24307696 | 0.69 | FABP3 (0.41) | FABP3FABP4FABP5TDP1 | |
| SCHEMBL8962537 | 0.68 | LMNA (0.46) | — | |
| SCHEMBL6204480 | 0.66 | SRC (0.67) | SRCPTPN1PTPN6PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996019446-A1 | β-CARBOXY SULFONAMIDE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1996-06-27 | — | — | WO | disclosed |
| US-5491170-A | TREATMENT OF HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-02-13 | — | — | US | disclosed |