Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962989 | 0.87 | KMT2A (0.48) | KMT2ALMNAMEN1 | |
| SCHEMBL8962450 | 0.76 | SRC (0.45) | SOAT1 | |
| SCHEMBL8962444 | 0.74 | SOAT2 (0.41) | KMT2ALMNASOAT1 | |
| SCHEMBL8962536 | 0.72 | SOAT1 (0.44) | KMT2ALMNASOAT1 | |
| SCHEMBL8962537 | 0.72 | LMNA (0.46) | KMT2ALMNA | |
| SCHEMBL9391001 | 0.70 | LMNA (0.44) | KMT2ALMNA | |
| SCHEMBL11234113 | 0.69 | L3MBTL1 (0.63) | KMT2ALMNAL3MBTL1 | |
| SCHEMBL8962517 | 0.69 | KMT2A (0.40) | KMT2ALMNAMEN1SOAT1 | |
| SCHEMBL7567348 | 0.69 | — | — | |
| SCHEMBL7082105 | 0.68 | NLRP3 (0.50) | KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491170-A | TREATMENT OF HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-02-13 | — | — | US | disclosed |