Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962429 | 0.91 | — | — | |
| SCHEMBL8962537 | 0.78 | LMNA (0.46) | NLRP3 | |
| SCHEMBL8962780 | 0.75 | — | — | |
| SCHEMBL24394204 | 0.68 | L3MBTL1 (0.62) | L3MBTL1 | |
| SCHEMBL7104643 | 0.67 | — | — | |
| SCHEMBL9450951 | 0.67 | NLRP3 (0.57) | NLRP3 | |
| SCHEMBL7082105 | 0.66 | NLRP3 (0.50) | NLRP3 | |
| SCHEMBL8962550 | 0.66 | NLRP3 (0.58) | MAPK1NLRP3 | |
| SCHEMBL8962422 | 0.65 | LMNA (0.44) | — | |
| SCHEMBL8962531 | 0.65 | SMN1; SMN2 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996019446-A1 | β-CARBOXY SULFONAMIDE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1996-06-27 | — | — | WO | claimed |
| WO-1996019446-A1 | β-CARBOXY SULFONAMIDE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1996-06-27 | — | — | WO | disclosed |
| US-5491170-A | TREATMENT OF HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-02-13 | — | — | US | disclosed |