Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 4/20 | 0.35 |
| ▸ | TPSD1 | Q9BZJ3 | 4/20 | 0.35 |
| ▸ | TPSG1 | Q9NRR2 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL170540 | 0.97 | LMNA (0.41) | LMNAMAPTNPSR1HDAC3HDAC1 | |
| SCHEMBL28392745 | 0.95 | HDAC3 (0.41) | LMNAMAPTNPSR1HDAC3HDAC1 | |
| SCHEMBL28397359 | 0.95 | HDAC3 (0.41) | LMNAMAPTNPSR1HDAC3HDAC1 | |
| SCHEMBL28528392 | 0.89 | ALDH1A1 (0.39) | LMNAMAPTNPSR1SMN1; SMN2KDM4E | |
| SCHEMBL4439473 | 0.88 | HDAC3 (0.37) | LMNAMAPTNPSR1HDAC3HDAC1 | |
| SCHEMBL4560033 | 0.88 | MEN1 (0.43) | LMNAMAPTNPSR1TSHR | |
| SCHEMBL8518592 | 0.84 | ALDH1A1 (0.49) | LMNAMAPTNPSR1HDAC3HDAC1 | |
| SCHEMBL2445561 | 0.84 | MEN1 (0.40) | LMNAMAPTTSHRSMN1; SMN2KDM4E | |
| SCHEMBL170857 | 0.83 | LMNA (0.42) | LMNAMAPTNPSR1HDAC3HDAC1 | |
| SCHEMBL17351915 | 0.81 | L3MBTL1 (0.49) | LMNAMAPTALDH1A1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0515553-B1 | OXYGEN BARRIER | EXXON CHEMICAL PATENTS INC (US) | 1996-02-07 | — | — | EP | disclosed |
| US-5391640-A | A molding material blends consisting of a polyamide or a polylactam homopolymer and a polyamide copolymer which has aminoalkanoic acids, diamines and dicarboxylic acids monomer; vapor barriers; waterproofing, permselectivity | ALLIEDSIGNAL INC. (US) | 1995-02-21 | — | — | US | disclosed |
| EP-0636161-A1 | MISCIBLE THERMOPLASTIC COMPOSITIONS CONTAINING POLYAMIDE/AMORPHOUS POLYAMIDE BLENDS. | ALLIED SIGNAL INC (US) | 1995-02-01 | — | — | EP | disclosed |
| WO-1993021276-A1 | MISCIBLE THERMOPLASTIC COMPOSITIONS CONTAINING POLYAMIDE/AMORPHOUS POLYAMIDE BLENDS | ALLIED-SIGNAL INC. (US) | 1993-10-28 | — | — | WO | disclosed |
| US-5093466-A | Food packaging | EXXON CHEMICAL PATENTS INC. (US) | 1992-03-03 | — | — | US | disclosed |
| WO-1991013113-A1 | OXYGEN BARRIER | EXXON CHEMICAL PATENTS INC. (US) | 1991-09-05 | — | — | WO | disclosed |