Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | CASP4 | P49662 | 2/20 | 0.44 |
| ▸ | CASP5 | P51878 | 2/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3556149 | 0.81 | LMNA (0.50) | ALDH1A1KDM4ESMN1; SMN2LMNAHTT | |
| SCHEMBL3476846 | 0.79 | CASP1 (0.50) | ALDH1A1KDM4EKMT2ATHRBGAA | |
| SCHEMBL2773991 | 0.78 | CXCR4 (0.50) | KDM4EKMT2ATHRBGAASMN1; SMN2 | |
| SCHEMBL9215848 | 0.78 | HRH4 (0.56) | ALDH1A1GLAKDM4EKMT2ATHRB | |
| SCHEMBL2770551 | 0.78 | ALDH1A1 (0.48) | ALDH1A1GLAKDM4EKMT2ATHRB | |
| SCHEMBL14503351 | 0.77 | LMNA (0.62) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL9640164 | 0.75 | KMT2A (0.69) | ALDH1A1KDM4EKMT2ATHRBMEN1 | |
| SCHEMBL9640988 | 0.75 | KMT2A (0.69) | ALDH1A1KDM4EKMT2ATHRBMEN1 | |
| SCHEMBL3475816 | 0.75 | HRH4 (0.46) | ALDH1A1GLAKDM4EKMT2ATHRB | |
| SCHEMBL9639621 | 0.74 | KMT2A (0.67) | ALDH1A1KDM4EKMT2ATHRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502187-A | Pharmaceutically active bicyclic-heterocyclic amines | THE UPJOHN COMPANY (US) | 1996-03-26 | — | — | US | claimed |